ArticleFrontiers in chemistry2019
Nanoparticles of Metal-Organic Cages Overcoming Drug Resistance in Ovarian Cancer.
Article in Frontiers in chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Potential Activity of Non-Platinum Metal-Based Organic Complexes Against Different Cancer Cell Types.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Reduced-Symmetry Homoleptic PdChemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Comparing organic and metallo-organic hydrazone molecular cages as potential carriers for doxorubicin delivery.Chemical science · 2024Article
- Water-Soluble Molecular Cages for Biological Applications.Molecules (Basel, Switzerland) · 2024Review
- Metal-organic cage as a theranostic nanoplatform for magnetic resonance imaging guided chemodynamic therapy.Theranostics · 2024Article
- Platinum Nanoparticles in Biomedicine: Preparation, Anti-Cancer Activity, and Drug Delivery Vehicles.Frontiers in pharmacology · 2022Review
- Recent developments in the construction and applications of platinum-based metallacycles and metallacages via coordination.Chemical Society reviews · 2020Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A long-standing challenge in the treatment of ovarian cancer is drug resistance to standard platinum-based chemotherapy. Recently, increasing attention has been drawn to the use of self-assembled metal-organic complexes as novel therapeutics for cancer treatment. However, high hydrophobicity that is often associated with these structures lowers their solubility and hinders their clinical translation. In this article, we present a proof-of-concept study of using nanoprecipitation to formulate the hydrophobic metal-organic cages and facilitate their use in treating chemoresistant ovarian cancer. The Pt
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Registered trials
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