ArticleBiomedical optics express2019
Time domain X-ray luminescence computed tomography: numerical simulations.
Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- Correlation between X-ray tube current exposure time and X-ray photon number in GATE.Journal of X-ray science and technology · 2022Article
- Radiation dose estimation for pencil beam X-ray luminescence computed tomography imaging.Journal of X-ray science and technology · 2021Article
- A Finite Element Mesh Regrouping Strategy-Based Hybrid Light Transport Model for Enhancing the Efficiency and Accuracy of XLCT.Frontiers in oncology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
X-ray luminescence computed tomography (XLCT) has the potential to image the biodistribution of nanoparticles inside deep tissues. In XLCT, X-ray excitable nanophosphors emit optical photons for tomographic imaging. The lifetime of the nanophosphor signal, rather than its intensity, could be used to extract biological microenvironment information such as oxygenation in deep tumors. In this study, we propose the design, the forward model, and the reconstruction algorithm of a time domain XLCT for lifetime imaging with high spatial resolution. We have investigated the feasibility of the proposed design with numerical simulations. We found that the reconstructed lifetime images are robust to noise levels up to 5% and to unknown optical properties up to 4 times of absorption and scattering coefficients.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.