Evidence map›Paper›PMID 30775090›Full record

ArticleBiomedical optics express2019

Novel window for cancer nanotheranostics: non-invasive ocular assessments of tumor growth and nanotherapeutic treatment efficacy

Mayank Goswami, Xinlei Wang, Pengfei Zhang, Wenwu Xiao, Sarah J Karlen, Yuanpei Li, Robert J Zawadzki, Marie E Burns, Kit S Lam, Edward N Pugh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Progress in MultimodalBiomedical optics express · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Mayank GoswamiEyePod Small Animal Ocular Imaging Laboratory, University of California, Davis, CA 95616, USA.
Xinlei WangDepartment of Cell Biology and Human Anatomy, University of California, Davis, CA 95616, USA.
Pengfei ZhangEyePod Small Animal Ocular Imaging Laboratory, University of California, Davis, CA 95616, USA.
Wenwu XiaoDepartment of Biochemistry and Molecular Medicine and Comprehensive Cancer Center, University of California, Davis, Sacramento, CA 95817, USA.
Sarah J KarlenDepartment of Cell Biology and Human Anatomy, University of California, Davis, CA 95616, USA.
Yuanpei LiDepartment of Biochemistry and Molecular Medicine and Comprehensive Cancer Center, University of California, Davis, Sacramento, CA 95817, USA.
Robert J ZawadzkiEyePod Small Animal Ocular Imaging Laboratory, University of California, Davis, CA 95616, USA.
Marie E BurnsDepartment of Cell Biology and Human Anatomy, University of California, Davis, CA 95616, USA.
Kit S LamDepartment of Biochemistry and Molecular Medicine and Comprehensive Cancer Center, University of California, Davis, Sacramento, CA 95817, USA.
Edward N PughEyePod Small Animal Ocular Imaging Laboratory, University of California, Davis, CA 95616, USA.
University of California, Davis · USEye Care Associates · USAdvanced Vision Institute · USIndian Institute of Technology Roorkee · INKR Mangalam University · IN

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Gina M Dayton · 2002 to 2026
$84.9M
VISION RESEARCH CORE GRANTP30EY012576 · NEI · UNIVERSITY OF CALIFORNIA DAVIS · PI MARIE E BURNS · 1999 to 2026
$18.9M
Theranostics of Photoreceptor-RPE-Choroid Neurovascular Unit in Mouse Models of Eye DiseasesR01EY026556 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Robert J Zawadzki · 2017 to 2026
$4.1M
Microglial Activation during Photoreceptor DegenerationR01EY024320 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BURNS, MARIE E · 2015 to 2024
$3.7M
The rodent eye as a non-invasive window for understanding cancer nanotherapeuticsU01CA198880 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LAM, KIT S · 2015 to 2019
$2.9M
Stimuli-responsive crosslinked theranostics against advanced prostate cancerR01CA199668 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LI, YUANPEI · 2015 to 2019
$1.8M
Smart targeting nano-theranostics for image-guided drug delivery to pediatric brain tumorsR01HD086195 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LI, YUANPEI · 2016 to 2020
$1.6M
NCI NIH HHS P30 CA093373NCI NIH HHS R01 CA199668NCI NIH HHS U01 CA198880NEI NIH HHS P30 EY012576NEI NIH HHS R01 EY024320NEI NIH HHS R01 EY026556NICHD NIH HHS R01 HD086195
6 · The paper itself

Abstract

In cancer research there is a fundamental need for animal models that allow the

Identifiers

PMID30775090
PMCPMC6363190
OpenAlexW2904119301

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.