ArticleBiomedical optics express2019
Fast, volumetric live-cell imaging using high-resolution light-field microscopy.
Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed.
- Three-dimensional imaging flow cytometry: current trends and future perspectives.Lab on a chip · 2026Review
- Fast 3D dynamic visualization of porcine spermatozoa by using high-resolution wavefront coding light sheet microscopy and machine learning.Scientific reports · 2026Article
- Single-shot extended-depth-of-field fourier light field microscopy enabled by a distorted grating.Biomedical optics express · 2026Article
- Review
- Highly sensitive volumetric single-molecule imaging.Nanophotonics (Berlin, Germany) · 2024Article
- Multifocal fluorescence video-rate imaging of centimetre-wide arbitrarily shaped brain surfaces at micrometric resolution.Nature biomedical engineering · 2024Article
- A head-mounted photoacoustic fiberscope for hemodynamic imaging in mobile mice.Light, science & applications · 2024Article
- Bioluminescence as a functional tool for visualizing and controlling neuronal activityNeurophotonics · 2024Article
- Light-field flow cytometry for high-resolution, volumetric and multiparametric 3D single-cell analysis.Nature communications · 2024Article
- Video-rate 3D imaging of living cells using Fourier view-channel-depth light field microscopy.Communications biology · 2023Article
- Imagining the future of optical microscopy: everything, everywhere, all at once.Communications biology · 2023Review
- Article
- AutoDeconJ: a GPU-accelerated ImageJ plugin for 3D light-field deconvolution with optimal iteration numbers predicting.Bioinformatics (Oxford, England) · 2023Article
- Low-voltage driving high-resistance liquid crystal micro-lens with electrically tunable depth of field for the light field imaging system.Scientific reports · 2022Article
- GANscan: continuous scanning microscopy using deep learning deblurring.Light, science & applications · 2022Article
- Fourier light-field imaging of human organoids with a hybrid point-spread function.Biosensors & bioelectronics · 2022Article
- Wavefront engineered light needle microscopy for axially resolved rapid volumetric imaging.Biomedical optics express · 2022Article
- Background inhibited and speed-loss-free volumetric imagingFrontiers in neuroscience · 2022Article
- Computational optical sectioning with an incoherent multiscale scattering model for light-field microscopy.Nature communications · 2021Article
- 2.5D microscopy with polarization independent SLM for enhanced detection efficiency and aberration correction.Optics express · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Visualizing diverse anatomical and functional traits that span many spatial scales with high spatio-temporal resolution provides insights into the fundamentals of living organisms. Light-field microscopy (LFM) has recently emerged as a scanning-free, scalable method that allows for high-speed, volumetric functional brain imaging. Given those promising applications at the tissue level, at its other extreme, this highly-scalable approach holds great potential for observing structures and dynamics in single-cell specimens. However, the challenge remains for current LFM to achieve a subcellular level, near-diffraction-limited 3D spatial resolution. Here, we report high-resolution LFM (HR-LFM) for live-cell imaging with a resolution of 300-700 nm in all three dimensions, an imaging depth of several micrometers, and a volume acquisition time of milliseconds. We demonstrate the technique by imaging various cellular dynamics and structures and tracking single particles. The method may advance LFM as a particularly useful tool for understanding biological systems at multiple spatio-temporal levels.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.