Evidence map›Paper›PMID 30775035›Full record

ArticleAntibodies (Basel, Switzerland)2018

A Collection of Single-Domain Antibodies that Crowd Ricin Toxin's Active Site.

Siva Krishna Angalakurthi, David J Vance, Yinghui Rong, Chi My Thi Nguyen, Michael J Rudolph, David Volkin, C Russell Middaugh, David D Weis, Nicholas J Mantis

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antibodies (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. A Rapid and Modular Nanobody Assay for Plug-and-Play Antigen Detection.bioRxiv : the preprint server for biology · 2025
    Article
  4. B Cell Epitope Mapping by High-Density Competition ELISAs.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  5. Article
  6. Article
  7. Special Issue: Nanobody.Antibodies (Basel, Switzerland) · 2020
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Siva Krishna AngalakurthiDepartment of Pharmaceutical Chemistry and Macromolecule and Vaccine Stabilization Center, University of Kansas, Lawrence, KS 660451, USA; s214a774@ku.edu (S.K.A.); volkin@ku.edu (D.V.); middaugh@ku.edu (C.R.M.).
David J VanceDivision of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, NY 12208, USA; david.vance@health.ny.gov (D.J.V.); yinghui.rong@health.ny.gov (Y.R.).ORCID 0000-0002-9913-7722
Yinghui RongDivision of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, NY 12208, USA; david.vance@health.ny.gov (D.J.V.); yinghui.rong@health.ny.gov (Y.R.).
Chi My Thi NguyenNew York Structural Biology Center (NYSBC), New York, NY 10027, USA; ntchimy@gmail.com (C.M.T.N.); mrudolph@nysbc.org (M.J.R.).
Michael J RudolphNew York Structural Biology Center (NYSBC), New York, NY 10027, USA; ntchimy@gmail.com (C.M.T.N.); mrudolph@nysbc.org (M.J.R.).
David VolkinDepartment of Pharmaceutical Chemistry and Macromolecule and Vaccine Stabilization Center, University of Kansas, Lawrence, KS 660451, USA; s214a774@ku.edu (S.K.A.); volkin@ku.edu (D.V.); middaugh@ku.edu (C.R.M.).
C Russell MiddaughDepartment of Pharmaceutical Chemistry and Macromolecule and Vaccine Stabilization Center, University of Kansas, Lawrence, KS 660451, USA; s214a774@ku.edu (S.K.A.); volkin@ku.edu (D.V.); middaugh@ku.edu (C.R.M.).
David D WeisDepartment of Chemistry and Ralph Adams Institute for Bioanalytical Chemistry, University of Kansas, Lawrence, KS 660451, USA; dweis@ku.edu.ORCID 0000-0003-3032-1211
Nicholas J MantisDivision of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, NY 12208, USA; david.vance@health.ny.gov (D.J.V.); yinghui.rong@health.ny.gov (Y.R.).ORCID 0000-0002-5083-8640
University of Kansas · USNew York State Department of Health · USNew York Structural Biology Center · US

Funding

NIAID NIH HHS HHSN272201400021C
6 · The paper itself

Abstract

In this report, we used hydrogen exchange-mass spectrometry (HX-MS) to identify the epitopes recognized by 21 single-domain camelid antibodies (V

Indexed as

antibodybiodefensecamelidhydrogen exchange-mass spectrometrytoxinvaccine

Identifiers

PMID30775035
PMCPMC6374049
OpenAlexW2903879052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.