Evidence map›Paper›PMID 30774901›Full record

ArticleChemical science2019

Nucleotide and structural label identification in single RNA molecules with quantum tunneling spectroscopy.

Gary R Abel, Lee E Korshoj, Peter B Otoupal, Sajida Khan, Anushree Chatterjee, Prashant Nagpal

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Gary R AbelDepartment of Chemical and Biological Engineering , University of Colorado Boulder , USA . Email: pnagpal@colorado.edu.
Lee E KorshojDepartment of Chemical and Biological Engineering , University of Colorado Boulder , USA . Email: pnagpal@colorado.edu.
Peter B OtoupalDepartment of Chemical and Biological Engineering , University of Colorado Boulder , USA . Email: pnagpal@colorado.edu.
Sajida KhanDepartment of Chemical and Biological Engineering , University of Colorado Boulder , USA . Email: pnagpal@colorado.edu.
Anushree ChatterjeeDepartment of Chemical and Biological Engineering , University of Colorado Boulder , USA . Email: pnagpal@colorado.edu.
Prashant NagpalDepartment of Chemical and Biological Engineering , University of Colorado Boulder , USA . Email: pnagpal@colorado.edu.ORCID 0000-0002-7966-2554
Energy Institute · GBUniversity of Colorado Boulder · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although a number of advances have been made in RNA sequencing and structural characterization, the lack of a method for directly determining the sequence and structure of single RNA molecules has limited our ability to probe heterogeneity in gene expression at the level of single cells. Here we present a method for direct nucleotide identification and structural label mapping of single RNA molecules

Identifiers

PMID30774901
PMCPMC6346406
OpenAlexW2899921476

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.