Evidence map›Paper›PMID 30774895›Full record

ArticleChemical science2019

Chemical and photochemical DNA "gears" reversibly control stiffness, shape-memory, self-healing and controlled release properties of polyacrylamide hydrogels.

Xia Liu, Junji Zhang, Michael Fadeev, Ziyuan Li, Verena Wulf, He Tian, Itamar Willner

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 142 citations in OpenAlex.

  1. Review
  2. Nucleic Acid-Modified Nanoparticles for Cancer Therapeutic Applications.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Chemical and Photochemical-Driven Dissipative FeJournal of the American Chemical Society · 2024
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. PhotocleavableChemical reviews · 2023
    Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 4 countries.

Xia LiuInstitute of Chemistry , The Center for Nanoscience and Nanotechnology , The Hebrew University of Jerusalem , Jerusalem , 91904 , Israel . Email: willnea@vms.huji.ac.il ; ; Tel: +972-2-6585272.
Junji ZhangKey Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering , Feringa Nobel Prize Scientist Joint Research Center , School of Chemistry and Molecular Engineering , East China University of Science & Technology , 130 Meilong Road , Shanghai 200237 , China.ORCID 0000-0003-2823-4637
Michael FadeevInstitute of Chemistry , The Center for Nanoscience and Nanotechnology , The Hebrew University of Jerusalem , Jerusalem , 91904 , Israel . Email: willnea@vms.huji.ac.il ; ; Tel: +972-2-6585272.
Ziyuan LiKey Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering , Feringa Nobel Prize Scientist Joint Research Center , School of Chemistry and Molecular Engineering , East China University of Science & Technology , 130 Meilong Road , Shanghai 200237 , China.
Verena WulfInstitute of Chemistry , The Center for Nanoscience and Nanotechnology , The Hebrew University of Jerusalem , Jerusalem , 91904 , Israel . Email: willnea@vms.huji.ac.il ; ; Tel: +972-2-6585272.
He TianKey Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering , Feringa Nobel Prize Scientist Joint Research Center , School of Chemistry and Molecular Engineering , East China University of Science & Technology , 130 Meilong Road , Shanghai 200237 , China.
Itamar WillnerInstitute of Chemistry , The Center for Nanoscience and Nanotechnology , The Hebrew University of Jerusalem , Jerusalem , 91904 , Israel . Email: willnea@vms.huji.ac.il ; ; Tel: +972-2-6585272.ORCID 0000-0001-9710-9077
Hebrew University of Jerusalem · ILEast China University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new class of stimuli-responsive DNA-based polyacrylamide hydrogels is described. They consist of glucosamine-boronate ester-crosslinked polyacrylamide chains being cooperatively bridged by stimuli-responsive nucleic acids. The triggered closure and dissociation of the stimuli-responsive units lead to switchable stiffness properties of the hydrogel. One hydrogel includes glucosamine-boronate esters and K

Identifiers

PMID30774895
PMCPMC6346408
OpenAlexW2898799517

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.