Evidence map›Paper›PMID 30774857›Full record

ArticleMedChemComm2019

Evaluation of novel

Omobolanle J Jesumoroti, Faridoon, Dumisani Mnkandhla, Michelle Isaacs, Heinrich C Hoppe, Rosalyn Klein

Abstract read
In one paragraph

Article in MedChemComm, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Benzo[ACS omega · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Frontiers in chemistry · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Omobolanle J JesumorotiDepartment of Chemistry , Rhodes University , Grahamstown , 6140 , South Africa . Email: r.klein@ru.ac.za.ORCID 0000-0001-6152-9467
FaridoonDepartment of Chemistry , Rhodes University , Grahamstown , 6140 , South Africa . Email: r.klein@ru.ac.za.ORCID 0000-0002-9460-4352
Dumisani MnkandhlaDepartment of Biochemistry and Microbiology , Rhodes University , Grahamstown , 6140 , South Africa.ORCID 0000-0001-6874-3677
Michelle IsaacsDepartment of Biochemistry and Microbiology , Rhodes University , Grahamstown , 6140 , South Africa.
Heinrich C HoppeDepartment of Biochemistry and Microbiology , Rhodes University , Grahamstown , 6140 , South Africa.ORCID 0000-0003-4409-1955
Rosalyn KleinDepartment of Chemistry , Rhodes University , Grahamstown , 6140 , South Africa . Email: r.klein@ru.ac.za.ORCID 0000-0002-9859-3507
Rhodes University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In an attempt to identify potential new agents that are active against HIV-1 IN, a series of novel coumarin-3-carbohydrazide derivatives were designed and synthesised. The toxicity profiles of these compounds showed that they were non-toxic to human cells and they exhibited promising anti-HIV-1 IN activities with IC

Identifiers

PMID30774857
PMCPMC6350760
OpenAlexW2905392488

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.