ReviewDrugs in context2019
Medication adherence and treatment-resistant hypertension: a review.
Review in Drugs in context, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic Review Article: New Drug Strategies for Treating Resistant Hypertension-the Importance of a Mechanistic, Personalized Approach.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024Pooled it
- Catheter-based ultrasound renal denervation in patients with resistant hypertension: the randomized, controlled REQUIRE trial.Hypertension research : official journal of the Japanese Society of Hypertension · 2022Trial
- Trial
- Qualitative insights into the experiences and goals of people living with severe difficult-to-treat hypertension in Australia.BMC cardiovascular disorders · 2026Article
- Obstructive sleep apnoea and hypertension: Current understanding, diagnosis and management.Clinical medicine (London, England) · 2026Review
- Partial non-adherence to antidiabetic therapy undermines diabetes management and correlates with treatment complexity: A cross-sectional study using blood plasma analysis.Diabetes, obesity & metabolism · 2026Article
- Mortality among individuals with chronic kidney disease based on the 2012 and 2021 KDIGO blood pressure targets.Scientific reports · 2025Article
- Effectiveness of the knowledge, attitude, practice intervention model in the management of hypertension in the elderly.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Supporting General Practitioners and people with hypertension to maximise medication use to control blood pressure: the contribution of Collective Intelligence to the development of the 'Maximising Adherence, Minimising Inertia' (MIAMI) intervention.Health psychology and behavioral medicine · 2024Article
- Prevalence, Risk Factors and Cardiovascular Comorbidities of Resistant Hypertension among Treated Hypertensives in a Nigerian Population.Global heart · 2024Article
- Factors predicting medication adherence among coronary artery disease patients in Saudi Arabia: A descriptive study.Saudi medical journal · 2023Article
- The association between drug therapy problems and blood pressure control of patients with hypertension in public health center setting.Journal of public health in Africa · 2023Article
- Towards an integrated blood pressure self-monitoring solution for stroke/TIA in Ireland: a mixed methods feasibility study for the TASMIN5S IRL randomised controlled trial.Pilot and feasibility studies · 2023Article
- Factors Influencing Medication Adherence in Elderly Patients with Hypertension: A Single Center Study in Western China.Patient preference and adherence · 2023Article
- The effect of the multimodal intervention on blood pressure in patients with first ischemic stroke: A randomized controlled trial.Belitung nursing journal · 2023Article
- Article
- Barriers and Solutions to Improve Therapeutic Adherence from the Perspective of Primary Care and Hospital-Based Physicians.Patient preference and adherence · 2022Article
- Is the KDIGO Systolic Blood Pressure Target <120 mm Hg for Chronic Kidney Disease Appropriate in Routine Clinical Practice?Hypertension (Dallas, Tex. : 1979) · 2022Review
- Medication Adherence and Treatment-Resistant Hypertension in Newly Treated Hypertensive Patients in the United Arab Emirates.Journal of clinical medicine · 2021Article
- Factors That Influence Adherence to Medication in Adults With Congenital Heart Disease (ACHD).Frontiers in psychiatry · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nonadherence is a common reason for treatment failure and treatment resistance. No matter how it is defined, it is a major issue in the management of chronic illnesses. There are numerous methods to assess adherence, each with its own strengths and weaknesses; however, no single method is considered the best. Nonadherence is common in patients with hypertension, and it is present in a large proportion of patients with uncontrolled blood pressure taking three or more antihypertensive agents. Availability of procedure-based treatment options for these patients has shed further light on this important issue with development of new methods to assess adherence. There is, however, no consensus on the management of nonadherence, which reflects the complex interplay of factors responsible for it.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.