Evidence map›Paper›PMID 30774684›Full record

ArticleIranian journal of pathology2018

Relationship Between PIK3CA Amplification and P110α and CD34 Tissue Expression as Angiogenesis Markers in Iranian Women with Sporadic Breast Cancer.

Shadi Hosseini, Farkhondeh Behjati, Maryam Rahimi, Nazanin Taheri, Hamidreza Khoram Khorshid, Fatemeh Aghakhani Moghaddam, Saghar Ghasemi, Masoud Karimlou, Fereidoon Sirati, Elahe Keyhani

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In one paragraph

Article in Iranian journal of pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Shadi HosseiniGenetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Farkhondeh BehjatiGenetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Maryam RahimiGenetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Nazanin TaheriGenetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Hamidreza Khoram KhorshidGenetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Fatemeh Aghakhani MoghaddamGenetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Saghar GhasemiGenetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Masoud KarimlouDept. of Epidemiology and Biostatistics, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran.
Fereidoon SiratiCancer Institute, Tehran University of Medical Sciences, Tehran, Iran.
Elahe KeyhaniGenetics Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
University of Social Welfare and Rehabilitation Sciences · IRIslamic Azad University Medical Branch of Tehran · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveThe PI3K/AKT/mTOR pathway is known to play an important role in regulating angiogenesis both in normal and breast cancer (BC) tissues.

methodsDNA samples were extracted from paraffin embedded tumor tissue blocks and copy number changes were evaluated by MLPA Technique. The results were analyzed by coffalyzer software. The tissue expression of P110α and CD34 was assessed using immunohistochemistry.

resultsTen out of 40 samples (17.5%) showed amplification in

conclusionNo significant association was detected between gain of

Indexed as

AmplificationBreast cancerMVDP110αPIK3CA

Identifiers

PMID30774684
PMCPMC6358562
OpenAlexW2897537454

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.