ReviewNeural plasticity2019
How Early Experience Shapes Human Development: The Case of Psychosocial Deprivation.
Review in Neural plasticity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Heritability of Psychological Traits and Developmental Milestones in Infancy: A Systematic Review and Meta-analysis.JAMA network open · 2022Pooled it
- Early psychosocial deprivation alters the refinement of neural dynamics across adolescence.Proceedings of the National Academy of Sciences of the United States of America · 2026Trial
- Evaluation of a community health worker home visit intervention to improve child development in South Africa: A cluster-randomized controlled trial.PLoS medicine · 2023Trial
- Heightened sensitivity to the caregiving environment during adolescence: implications for recovery following early-life adversity.Journal of child psychology and psychiatry, and allied disciplines · 2021Trial
- Early parenting intervention accelerates inhibitory control development among CPS-involved children in middle childhood: A randomized clinical trial.Developmental science · 2021Trial
- Psychiatric outcomes following severe deprivation in early childhood: Follow-up of a randomized controlled trial at age 16.Journal of consulting and clinical psychology · 2020Trial
- Foster care promotes adaptive functioning in early adolescence among children who experienced severe, early deprivation.Journal of child psychology and psychiatry, and allied disciplines · 2018Trial
- The power of the group - Group-based parenting programmes for disadvantaged parents and their infants: a realist review.International journal of nursing studies advances · 2026Review
- Eyes on Development: Exploring the Impact of Early Life Nutrition Exposures on Child Cognition Through Eye-Tracking Assessment.Nutrition reviews · 2026Article
- Developmental Care in the Early Years in Pediatric Intensive Care Patients as a Strategy to Mitigate Pediatric Post-Intensive-Care Syndrome: A Narrative Review.Journal of intensive care medicine · 2026Review
- Experience-dependent development of vagal circuitry in rodents and humans.Neuroscience and biobehavioral reviews · 2026Review
- Advancing child health: forecasting the next great research achievements.Pediatric research · 2026Article
- Autism and immigration background, insights from a population-based study.Paediatrics & child health · 2026Article
- Early adversity alters brain architecture and increases susceptibility to mental health disorders.Nature reviews. Neuroscience · 2025Review
- Enhancing visitation in the child welfare system for children separated from their birth parents: pilot results of fostering relationships.Attachment & human development · 2025Article
- Cost-effectiveness analysis of two integrated early childhood development programs into Bangladeshi primary health-care services.The Lancet regional health. Southeast Asia · 2025Article
- Maternal alexithymia and caregiving behavior: the role of executive functioning - A FinnBrain Birth Cohort study.Archives of women's mental health · 2025Article
- The reciprocal relationship between social exclusion and basic psychological needs through cross-lagged analysis.Scientific reports · 2024Article
- Oncology Camp Participation and Psychosocial Health in Children Who Have Lived with Cancer-A Pilot Study.Current oncology (Toronto, Ont.) · 2024Article
- Probing the content of affective semantic memory following caregiving-related early adversity.Developmental science · 2024Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Experience plays an essential role in building brain architecture after birth. The question we address in this paper is what happens to brain and behavior when a young child is deprived of key experiences during critical periods of brain development. We focus in particular on the consequences of institutional rearing, with implication for the tens of millions of children around the world who from an early age experience profound psychosocial deprivation. Evidence is clear that deprivation can lead to a host of both short- and long-term consequences, including perturbations in brain structure and function, changes at cellular and molecular levels, and a plethora of psychological and behavioral impairments.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.