Evidence map›Paper›PMID 30774493›Full record

ReviewJournal of blood medicine2019

Residual risk of HIV, HCV, and HBV transmission by blood transfusion between 2015 and 2017 at the Regional Blood Transfusion Center of Ouagadougou, Burkina Faso.

Arzouma Paul Yooda, Salam Sawadogo, Serge Théophile Soubeiga, Dorcas Obiri-Yeboah, Koumpingnin Nebie, Abdoul Karim Ouattara, Birama Diarra, Abibou Simpore, Yetema Dieudonné Yonli, Abdoul-Guaniyi Sawadogo and 6 more

Abstract readReview
In one paragraph

Review in Journal of blood medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Prevalence and Residual Risk of HIV in Volunteer Blood Donors of Zhejiang Province, China, from 2018 to 2022.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Patient blood management and blood conservation - Complimentary concepts and solutions for blood establishments and clinical services in South Africa and beyond.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2021
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Arzouma Paul YoodaLaboratory of Molecular Biology and Genetics (LaBioGene), Training and Research Unit in Life and Earth Sciences, University Ouaga I Professor Joseph Ki-Zerbo, Ouagadougou, Burkina Faso, jacques.simpore@labiogene.org.
Salam SawadogoNational Blood Transfusion Center (NBTC), Ouagadougou, Burkina Faso.
Serge Théophile SoubeigaLaboratory of Molecular Biology and Genetics (LaBioGene), Training and Research Unit in Life and Earth Sciences, University Ouaga I Professor Joseph Ki-Zerbo, Ouagadougou, Burkina Faso, jacques.simpore@labiogene.org.
Dorcas Obiri-YeboahDepartment of Microbiology and Immunology, School of Medical Sciences, University of Cape Coast, Ghana.
Koumpingnin NebieNational Blood Transfusion Center (NBTC), Ouagadougou, Burkina Faso.
Abdoul Karim OuattaraLaboratory of Molecular Biology and Genetics (LaBioGene), Training and Research Unit in Life and Earth Sciences, University Ouaga I Professor Joseph Ki-Zerbo, Ouagadougou, Burkina Faso, jacques.simpore@labiogene.org.
Birama DiarraLaboratory of Molecular Biology and Genetics (LaBioGene), Training and Research Unit in Life and Earth Sciences, University Ouaga I Professor Joseph Ki-Zerbo, Ouagadougou, Burkina Faso, jacques.simpore@labiogene.org.
Abibou SimporeNational Blood Transfusion Center (NBTC), Ouagadougou, Burkina Faso.
Yetema Dieudonné YonliNational Blood Transfusion Center (NBTC), Ouagadougou, Burkina Faso.
Abdoul-Guaniyi SawadogoNational Blood Transfusion Center (NBTC), Ouagadougou, Burkina Faso.
Bia Emile DraboNational Blood Transfusion Center (NBTC), Ouagadougou, Burkina Faso.
Seimbou ZallaNational Blood Transfusion Center (NBTC), Ouagadougou, Burkina Faso.
Anita Pierrette SiritiéNational Blood Transfusion Center (NBTC), Ouagadougou, Burkina Faso.
Rodrigue Sosthène NanaNational Blood Transfusion Center (NBTC), Ouagadougou, Burkina Faso.
Honorine DahourouNational Blood Transfusion Center (NBTC), Ouagadougou, Burkina Faso.
Jacques SimporeLaboratory of Molecular Biology and Genetics (LaBioGene), Training and Research Unit in Life and Earth Sciences, University Ouaga I Professor Joseph Ki-Zerbo, Ouagadougou, Burkina Faso, jacques.simpore@labiogene.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn sub-Saharan Africa, the high endemicity of blood-borne infections is a serious threat to transfusion safety. In order to improve transfusion safety, Burkina Faso has undertaken in recent years a reorganization of its blood-transfusion system through the creation of a National Blood Transfusion Center, which is the only blood operator in the whole country. This study aimed to estimate the residual risk of transmission of HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV) by blood transfusion at the Regional Blood Transfusion Center (RBTC) of Ouagadougou.

methodsThis was a retrospective study conducted at the RBTC of Ouagadougou between 2015 and 2017. Prevalence of infectious markers was calculated for first-time donors and incidence rates calculated for repeat donors who had made at least two donations of blood over the study period. Residual risks were estimated for the three viruses (HIV, HBV, and HCV) by multiplying the incidence rate per 100,000 person-years by the respective durations of serological windows.

resultsBetween 2015 and 2017, of a total of 84,299 blood donors, 68,391 (81.13%) were first-time donors compared to 15,908 (18.87%) repeat donors. The seroprevalence of HBV (8.56%) was twice that of HCV (4.40%) and fourfold that of HIV (1.80%). Incidence rates were 1,215, 2,601, and 1,599 per 100,000 donations for HIV, HCV, and HBV, respectively. In contrast, the estimated residual risk for HCV (1 in 213 donations) was double that of HBV (1 in 408 donations) and four times that of HIV (1 in 1,366).

conclusionThe residual risk of transmission of these viruses by blood transfusion remains high in repeat donors. An effective donor-retention and education policy could help to reduce this residual risk.

Indexed as

incidenceinfectious diseasesprevalenceresidual transfusion risk

Identifiers

PMID30774493
PMCPMC6362960

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.