Evidence map›Paper›PMID 30774396›Full record

ArticleInfection and drug resistance2019

Comparative analysis of KPC-2-encoding chimera plasmids with multi-replicon IncR:Inc

Daofeng Qu, Yang Shen, Lingfei Hu, Xiaoyuan Jiang, Zhe Yin, Bo Gao, Yuee Zhao, Wenhui Yang, Huiying Yang, Jianzhong Han and 1 more

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 36 citations in OpenAlex.

  1. Persistent multispecies dissemination ofJournal of clinical microbiology · 2025
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  5. Molecular characterization of theFrontiers in veterinary science · 2024
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  6. Insight into the Mechanisms of Carbapenem Resistance inAntibiotics (Basel, Switzerland) · 2023
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  7. Article
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  9. Article
  10. Article
  11. Article
  12. Epidemiology of Plasmids inAntibiotics (Basel, Switzerland) · 2022
    Article
  13. Article
  14. Article
  15. Genomic Analysis of KPC-2-ProducingFrontiers in microbiology · 2022
    Article
  16. Molecular Analysis ofmSphere · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Prevalence ofPathogens (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Daofeng QuState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China, dongshengzhou1977@gmail.com.
Yang ShenSchool of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, China, hanjz99@mail.zjgsu.edu.cn.
Lingfei HuState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China, dongshengzhou1977@gmail.com.
Xiaoyuan JiangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China, dongshengzhou1977@gmail.com.
Zhe YinState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China, dongshengzhou1977@gmail.com.
Bo GaoState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China, dongshengzhou1977@gmail.com.
Yuee ZhaoState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China, dongshengzhou1977@gmail.com.
Wenhui YangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China, dongshengzhou1977@gmail.com.
Huiying YangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China, dongshengzhou1977@gmail.com.
Jianzhong HanSchool of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, China, hanjz99@mail.zjgsu.edu.cn.
Dongsheng ZhouState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China, dongshengzhou1977@gmail.com.
Institute of Microbiology · BYZhejiang Gongshang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncR, IncFII, IncpA1763-KPC, and IncN1 plasmids have been increasingly found among

methodsPlasmids p721005-KPC, p504051-KPC, and pA3295-KPC were fully sequenced and compared with previously sequenced related plasmids pHN84KPC (IncR), pKPHS2 (IncFII

resultsThe backbone of p721005-KPC/p504051-KPC was a hybrid of the entire 10-kb IncR-type backbone from pHN84KPC, the entire 64.3-kb IncFII

conclusionIn each of p721005-KPC, p504051-KPC, and pA3295-KPC, multiple replicons in coordination with maintenance and conjugation regions of various origins would maintain a broad host range and a stable replication at a steady-state plasmid copy number.

Indexed as

blaKPC-2mobile elementsmulti-drug resistancemulti-replicon plasmids

Identifiers

PMID30774396
PMCPMC6353027
OpenAlexW2913998817

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.