Evidence map›Paper›PMID 30774359›Full record

ArticleOncoTargets and therapy2019

Anticancer activity of 1,25-(OH)

Wei Zheng, Lin Cao, Linna Ouyang, Qian Zhang, Bofeng Duan, Wei Zhou, Shan Chen, Wei Peng, Yi Xie, Qing Fan and 1 more

Open access · goldAbstract read
In one paragraph

Article in OncoTargets and therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. The role of vitamin D signalling in β cell apoptosis: a systematic review.Apoptosis : an international journal on programmed cell death · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Wei ZhengDepartment of Thyroid and Breast Surgery, The Third People's Hospital of Shenzhen, Shenzhen, Guangdong 518112, China, sztphzhengwei@hotmail.com.
Lin CaoDepartment of Breast Surgery, Maternal and Child Health Care Hospital of Hunan Province, Changsha, Hunan 410008, China.
Linna OuyangDepartment of Thyroid and Breast Surgery, The Third People's Hospital of Shenzhen, Shenzhen, Guangdong 518112, China, sztphzhengwei@hotmail.com.
Qian ZhangSchool of Clinical Medicine, Xiangnan University, Chenzhou, Hunan 423000, China.
Bofeng DuanDepartment of Thyroid and Breast Surgery, The Third People's Hospital of Shenzhen, Shenzhen, Guangdong 518112, China, sztphzhengwei@hotmail.com.
Wei ZhouDepartment of Medical Examination, Zhuzhou Central Hospital, Zhuzhou, Hunan 412007, China.
Shan ChenDepartment of General Surgery, The Third Hospital of Changsha, Changsha, Hunan 410013, China.
Wei PengDepartment of Thyroid and Breast Surgery, The Third People's Hospital of Shenzhen, Shenzhen, Guangdong 518112, China, sztphzhengwei@hotmail.com.
Yi XieDepartment of Thyroid and Breast Surgery, The Third People's Hospital of Shenzhen, Shenzhen, Guangdong 518112, China, sztphzhengwei@hotmail.com.
Qing FanDepartment of Gastrointestinal and Breast and Thyroid Surgery, Changsha Hospital of Traditional Chinese Medicine (Changsha Eighth Hospital), Changsha, Hunan 410100, China.
Daoxing GongDepartment of Surgery, The Medical School, University of South China, Hengyang, Hunan 421000, China.
Shenzhen Third People’s Hospital · CNHunan Provincial Maternal and Child Health Hospital · CNThe Eighth Hospital of Xi'an · CNThird Hospital of Changsha · CNUniversity of South China · CNXiangnan University · CNZhuzhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBreast cancer is the most common cancer among women with ~1.67 million cases diagnosed annually worldwide, and ~1 in 37 women succumbed to breast cancer. Over the past decades, new therapeutic strategy has substantially improved the curative effect for women with breast cancer. However, the currently available ER-targeted and HER-2-based therapies are not effective for triple-negative breast cancer patients, which account for ~15% of total breast cancer cases. MATERIALS AND

methodsWe reported that 1,25-(OH)

resultsThe anticancer effect of 1,25-(OH)

conclusion1,25-(OH)

Indexed as

125-(OH)2D3breast cancercell apoptosiscell proliferationER-negative

Identifiers

PMID30774359
PMCPMC6348968
OpenAlexW2909567485

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.