Evidence map›Paper›PMID 30774322›Full record

Trial reportClinical interventions in aging2019

Investigating dose-response effects of multimodal exercise programs on health-related quality of life in older adults.

Navin Kaushal, Francis Langlois, Laurence Desjardins-Crépeau, Martin S Hagger, Louis Bherer

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Clinical interventions in aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06094413 (The Effects of an 8-week Multicomponent Training Program on Quality of Life, Fear of Falling, &Amp; Physical Performance in Community-Dwelling Older Adults), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06094413 nacompletednot on this mapstarted 2024, after this paper: background citation

The Effects of an 8-week Multicomponent Training Program on Quality of Life, Fear of Falling, &Amp; Physical Performance in Community-Dwelling Older Adults

TypeinterventionalSponsorGeisinger ClinicRan2024 to 2024Enrolled20ConditionsSarcopeniaArmsMulticomponent Training Intervention
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Navin KaushalDepartment of Medicine, University of Montreal, Montreal, Quebec, Canada, n.kaushal@umontreal.ca.
Francis LangloisCIUSSS de l'Estrie, Centre Hospitalier Universitaire de Sherbrooke, Montreal, Quebec, Canada.
Laurence Desjardins-CrépeauDepartment of Medicine, University of Montreal, Montreal, Quebec, Canada, n.kaushal@umontreal.ca.
Martin S HaggerSchool of Psychology and Speech Pathology, Faculty of Health Sciences, Curtin University, Perth, WA, Australia.
Louis BhererDepartment of Medicine, University of Montreal, Montreal, Quebec, Canada, n.kaushal@umontreal.ca.
Curtin University · AUMontreal Heart Institute · CACentre Hospitalier Universitaire de Sherbrooke · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOlder adults are at risk of multiple chronic diseases, most of which could be prevented by engaging in regular physical activity. Frailty is a state of increased vulnerability to diseases. Worsening symptoms of frailty, such as decrease in physical functionality, can compromise health-related quality of life (HR-QOL). Previous findings suggest that frailty moderates the relationship between physical activity and HR-QOL, yet intervention findings are limited, particularly in dose-response analyses. Hence, this study was conducted to test if lower-dose physical activity (120 minutes/week) would provide the same benefits in health outcomes (physical functionality and HR-QOL) as higher-dose physical activity (180 minutes/week).

methodsParticipants (n=110) were older adults comprising higher-dose, lower-dose, and control groups who were combined from recent randomized controlled trials. Experimental groups participated in a multimodal exercise program in a supervised laboratory setting for 12 weeks.

resultsThe higher-dose group showed a significant improvement in physical functionality (

conclusionThis study identifies a positive, predictive relationship between exercise duration and health outcomes (HR-QOL dimensions and frailty) among older adults. Frail individuals in the higher-dose group demonstrated significant recovery of capacity HR-QOL, thus reflecting improvement in their daily activities.

Indexed as

ExerciseQuality of LifeActivities of Daily LivingAgedAged, 80 and overExercise TherapyFemaleFrailtyHumansLinear ModelsMaleTime Factorsagingfrailtymultimodal exercisephysical activity

Identifiers

PMID30774322
PMCPMC6352872
OpenAlexW2915043271

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.