SynthesisDiagnostic and interventional radiology (Ankara, Turkey)2019
The utility of apparent diffusion coefficients for predicting treatment response to uterine arterial embolization for uterine leiomyomas: a systematic review and meta-analysis.
Synthesis in Diagnostic and interventional radiology (Ankara, Turkey), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Early Detection of Cell Death Using Transmembrane Water Exchange Magnetic Resonance Imaging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Understanding different aspects of blood supply of uterine fibroids: an overview of ultrasound and magnetic resonance imaging techniques.Insights into imaging · 2025Article
- Postoperative symptom changes following uterine artery embolization for uterine fibroid based on FIGO classification.CVIR endovascular · 2025Article
- Safety profile and technical success of narrow window CT-guided percutaneous biopsy with blunt needle approach in the abdomen and pelvis.European radiology · 2024Article
- Can pre-procedural MRI signal intensity ratio predict the success of uterine artery embolization in treatment of myomas?Turkish journal of medical sciences · 2021Article
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Authors and funding
3 authors.
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Abstract
purposeApparent diffusion coefficient (ADC) values, which are derived from diffusion-weighted imaging, have a potential role for predicting treatment response. A systematic review was conducted to examine the value of baseline ADC values for predicting leiomyoma size reduction after uterine arterial embolization (UAE).
methodsStudy selection, quality appraisal and data extraction were conducted independently by two authors. Statistical analyses included the calculation of weighted means and summary correlation coefficients (under the random effects model).
resultsEleven studies consisting of a total of 258 patients (age, weighted mean±standard deviation [SD], 43.1±10.1 years) were included. The weighted mean±SD ADC value was 1.2±1.5 ×10-3 s/mm2 at baseline (ten studies) and 1.3±2.8 ×10-3 s/mm2 at approximately 6 months after embolization (six studies). The weighted mean percentage leiomyoma volume reduction (VR) at 6 months was 47.1%±35.6% (seven studies). Based on four studies, the weighted summary correlation coefficient for the correlation between baseline ADC and leiomyoma VR at approximately 6 months was not significant (r=0.40; 95% CI, -0.07 to 0.72; I2=69.7%). No associations were found in three of the four studies that examined changes in ADC values as a predictor.
conclusionDue to high heterogeneity, it is unclear whether ADC may be useful for predicting treatment responses to UAE.
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