ArticleHuman brain mapping2019
Cognitive regulation of ventromedial prefrontal activity evokes lasting change in the perceived self-relevance of persuasive messaging.
Article in Human brain mapping, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04279483 (Geo Smoking Study and Neural and Geospatial Examination of Smokers' Exposure to Retail Environments), which is not on this map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Geo Smoking Study and Neural and Geospatial Examination of Smokers' Exposure to Retail Environments
Who cites it
14 citing papers in PubMed.
- The role of dorsal anterior cingulate cortex in dynamic attitude changes in naturalistic settings.Communications biology · 2026Article
- Brain activity explains message effectiveness: A mega-analysis of 16 neuroimaging studies.PNAS nexus · 2025Article
- Pictorial warning labels reduce sharing intentions, blunt self-relevance processes elicited by social media posts promoting cannabis edibles.The Journal of communication · 2025Article
- Behavioral interventions motivate action to address climate change.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- From Individual to Population: Circuit Organization of Pyramidal Tract and Intratelencephalic Neurons in Mouse Sensorimotor Cortex.Research (Washington, D.C.) · 2024Article
- If you're happy and you know it: neural correlates of self-evaluated psychological health and well-being.Social cognitive and affective neuroscience · 2023Article
- Brain system integration and message consistent health behavior change.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2022Article
- Brain and behavior in health communication: The Canadian COVID-19 Experiences Project.Brain, behavior, & immunity - health · 2022Article
- Sense or sensibility? The neuro-functional basis of the structural matching effect in persuasion.Cognitive, affective & behavioral neuroscience · 2020Article
- Media content sharing as a value-based decision.Current opinion in psychology · 2020Review
- The Effectiveness of Online Messages for Promoting Smoking Cessation Resources: Predicting Nationwide Campaign Effects From Neural Responses in the EX Campaign.Frontiers in human neuroscience · 2020Article
- Individual Differences in Brain Responses: New Opportunities for Tailoring Health Communication Campaigns.Frontiers in human neuroscience · 2020Article
- Neural valuation of antidrinking campaigns and risky peer influence in daily life.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2019Article
- Cognitive regulation of ventromedial prefrontal activity evokes lasting change in the perceived self-relevance of persuasive messaging.Human brain mapping · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Persuasive messages can change people's thoughts, feelings, and actions, but these effects depend on how people think about and appraise the meaning of these messages. Drawing from research on the cognitive control of emotion, we used neuroimaging to investigate neural mechanisms underlying cognitive regulation of the affective and persuasive impact of advertisements communicating the risks of binge drinking, a significant public health problem. Using cognitive control to up-regulate (vs. down-regulate) responses to the ads increased: negative affect related to consequences of excessive drinking, perceived ad effectiveness, and ratings of ad self-relevance made after a one-hour delay. Neurally, these effects of cognitive control were mediated by goal-congruent modulation of ventromedial prefrontal cortex and distributed brain patterns associated with negative emotion and subjective valuation. These findings suggest that people can leverage cognitive control resources to deliberately shape responses to persuasive appeals, and identify mechanisms of emotional reactivity and integrative valuation that underlie this ability. Specifically, brain valuation pattern expression mediated the effect of cognitive goals on perceived message self-relevance, suggesting a role for the brain's valuation system in shaping responses to persuasive appeals in a manner that persists over time.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.