Evidence map›Paper›PMID 30773695›Full record

ArticleInternational journal of geriatric psychiatry2019

Delirium and Alzheimer disease: A proposed model for shared pathophysiology.

Tamara G Fong, Sarinnapha M Vasunilashorn, Towia Libermann, Edward R Marcantonio, Sharon K Inouye

Abstract read
In one paragraph

Article in International journal of geriatric psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Observational
  8. Review
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  10. Clinical and intracranial electrophysiological signatures of post-operative and post-ictal delirium.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tamara G FongDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA.ORCID 0000-0001-8355-7047
Sarinnapha M VasunilashornHarvard Medical School, Boston, MA, USA.
Towia LibermannHarvard Medical School, Boston, MA, USA.
Edward R MarcantonioHarvard Medical School, Boston, MA, USA.
Sharon K InouyeAging Brain Center, Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA.

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
The Role of Inflammation in the Pathophysiology of Delirium and its Associated Long-Term Cognitive DeclineP01AG031720 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI SHAFI, MOUHSIN · 2010 to 2022
$26.7M
Advancing the Understanding of Postoperative Delirium Mechanisms via Multi-OmicsR01AG051658 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI TOWIA A. LIBERMANN, EDWARD R MARCANTONIO · 2016 to 2026
$5.9M
Supplement to Network for Investigation of Delirium across the U.S (NIDUS)R24AG054259 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI INOUYE, SHARON K. · 2016 to 2020
$4.3M
Mid-Career Mentoring Award for Patient-Oriented Research in AgingK24AG035075 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI MARCANTONIO, EDWARD R · 2010 to 2021
$1.9M
K07 Leadership GrantK07AG041835 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI INOUYE, SHARON K. · 2013 to 2017
$656k
Shared Pathophysiology of Postoperative Delirium and Alzheimer’s Disease and Related DementiasK01AG057836 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI VASUNILASHORN, SARINNAPHA · 2018 to 2022
$565k
Blood-based biomarkers of neuronal injury and Alzheimer's disease: predictors of delirium and long-term cognitive decline, and potential shared pathophysiologyR21AG057955 · NIA · HEBREW REHABILITATION CENTER FOR AGED · PI FONG, TAMARA G · 2017 to 2018
$471k
Genetic and Neuroinflammatory Mechanisms of Delirium and Alzheimer’s Disease and Related DementiasR03AG061582 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI VASUNILASHORN, SARINNAPHA · 2019 to 2020
$175k
NCATS NIH HHS UL1 TR001102NCATS NIH HHS UL1TR001102-04S2NIA NIH HHS K01 AG057836NIA NIH HHS K07 AG041835NIA NIH HHS K24 AG035075NIA NIH HHS P01 AG031720NIA NIH HHS R01 AG051658NIA NIH HHS R03 AG061582NIA NIH HHS R21 AG057955NIA NIH HHS R24 AG054259
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

biomarkersdeliriumdementia

Identifiers

PMID30773695
PMCPMC6830540

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.