Evidence map›Paper›PMID 30773505›Full record

ArticleMicrobes and environments2019

Point Mutations Lead to Increased Levels of c-di-GMP and Phenotypic Changes to the Colony Biofilm Morphology in Alcanivorax borkumensis SK2.

Manoj Prasad, Nozomu Obana, Kaori Sakai, Toshiki Nagakubo, Shun Miyazaki, Masanori Toyofuku, Jacques Fattaccioli, Nobuhiko Nomura, Andrew S Utada

Open access · diamondAbstract read
In one paragraph

Article in Microbes and environments, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Manoj PrasadFaculty of Life and Environmental Sciences, University of Tsukuba.
Nozomu ObanaTransborder Medical Research Center, Faculty of Medicine, University of Tsukuba.
Kaori SakaiPASTEUR, Département de chimie, École Normale Supérieure, PSL University, Sorbonne Université, CNRS.
Toshiki NagakuboFaculty of Life and Environmental Sciences, University of Tsukuba.
Shun MiyazakiSchool of Life and Environmental Sciences, University of Tsukuba.
Masanori ToyofukuFaculty of Life and Environmental Sciences, University of Tsukuba.
Jacques FattaccioliPASTEUR, Département de chimie, École Normale Supérieure, PSL University, Sorbonne Université, CNRS.
Nobuhiko NomuraFaculty of Life and Environmental Sciences, University of Tsukuba.
Andrew S UtadaFaculty of Life and Environmental Sciences, University of Tsukuba.
University of Tsukuba · JPInstitut Pierre-Gilles de Gennes pour la Microfluidique · FRUniversité Paris Sciences et Lettres · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcanivorax borkumensis is a ubiquitous marine bacterium that utilizes alkanes as a sole carbon source. We observed two phenotypes in the A. borkumensis SK2 type strain: rough (R) and smooth (S) types. The S type exhibited lower motility and higher polysaccharide production than the R type. Full genome sequencing revealed a mutation in the S type involved in cyclic-di-GMP production. The present results suggest that higher c-di-GMP levels in the S type control the biofilm forming behavior of this bacterium in a manner commensurate with other Gram-negative bacteria.

Indexed as

AlcanivoraceaeAlkanesBacterial ProteinsBiofilmsCyclic GMPGene Expression Regulation, BacterialGenome, BacterialPhenotypePoint MutationPolysaccharides, BacterialAlkanesBacterial Proteinsbis(3',5')-cyclic diguanylic acidCyclic GMPPolysaccharides, BacterialAlcanivoraxc-di-GMPhydrocarbonoclasticmarine microorganism

Identifiers

PMID30773505
PMCPMC6440734
OpenAlexW2911586367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.