ArticlePsychological medicine2020
Distinct temporal brain dynamics in bipolar disorder and schizophrenia during emotion regulation.
Article in Psychological medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- In search of convergent regional brain abnormality in cognitive emotion regulation: A transdiagnostic neuroimaging meta-analysis.Human brain mapping · 2022Pooled it
- Altered neural activities during emotion regulation in depression: a meta-analysis.Journal of psychiatry & neuroscience : JPNPooled it
- Effect of lithium administration on brain activity under an emotion regulation paradigm in healthy participants: a functional magnetic resonance imaging study.Psychopharmacology · 2023Trial
- Neurophysiological evidence for emotion regulation abnormalities in individuals at clinical high-risk for psychosis.European archives of psychiatry and clinical neuroscience · 2026Article
- Identifying transdiagnostic neurobiomarkers for precision major psychiatric disordersJournal of translational internal medicine · 2026Article
- Abnormal functional neurocircuitry underpinning emotional processing in fibromyalgia.European archives of psychiatry and clinical neuroscience · 2024Article
- Deconstructing emotion regulation in schizophrenia: The nature of abnormalities at the selection and implementation stages.Journal of psychopathology and clinical science · 2023Article
- A Randomized Clinical Trial to Assess the Effect of Medication Therapy Plus tDCS on Problem-solving and Emotion Regulation of Patients with Bipolar Disorder Type I.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2023Article
- Immediate visual reproduction negatively correlates with brain entropy of parahippocampal gyrus and inferior occipital gyrus in bipolar II disorder adolescents.BMC psychiatry · 2023Article
- Ecological Momentary Assessment Of State Fluctuations In Mindfulness And Symptoms In Psychotic Disorders.Journal of contextual behavioral science · 2023Article
- Emotion regulation in bipolar disorder type-I: multivariate analysis of fMRI data.International journal of bipolar disorders · 2023Article
- Examining the effects of teacher self-compassion, emotion regulation, and emotional labor strategies as predictors of teacher resilience in EFL context.Frontiers in psychology · 2023Article
- The longitudinal trajectory of emotion regulation and associated neural activity in patients with bipolar disorder: A prospective fMRI study.Acta psychiatrica Scandinavica · 2022Article
- Deconstructing emotion regulation in schizophrenia: the nature and consequences of abnormalities at the identification stage.European archives of psychiatry and clinical neuroscience · 2022Article
- Decomposition-Based Correlation Learning for Multi-Modal MRI-Based Classification of Neuropsychiatric Disorders.Frontiers in neuroscience · 2022Article
- Emotion Regulation, Effort and Fatigue: Complex Issues Worth Investigating.Frontiers in psychology · 2022Article
- Altered frontal cortex functioning in emotion regulation and hopelessness in bipolar disorder.Bipolar disorders · 2021Article
- Abnormalities in white matter tracts in the fronto-striatal-thalamic circuit are associated with verbal performance in 22q11.2DS.Schizophrenia research · 2020Article
- Neurophysiological evidence for emotion regulation impairment in schizophrenia: The role of visual attention and cognitive effort.Journal of abnormal psychology · 2020Article
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDisturbances in emotion regulation (ER) are characteristic of both patients with bipolar disorder (BD) and schizophrenia (SZ). We investigated the temporal dynamics of brain activation during cognitive ER in BD and SZ to understand the contribution of temporal characteristics of disturbed ER to their unique and shared symptomatology.
methodForty-six participants performed an ER-task (BD, n = 15; SZ, n = 16; controls, n = 15) during functional magnetic resonance imaging, in which they were instructed to use cognitive reappraisal techniques to regulate their emotional responses. Finite impulse response modeling was applied to estimate the temporal dynamics of brain responses during cognitive reappraisal (v. passive attending) of negative pictures. Group, time, and group × time effects were tested using multivariate modeling.
resultsWe observed a group × time interaction during ER in the ventrolateral prefrontal cortex (VLPFC), supplementary motor area (SMA) and inferior occipital gyrus. Patients with SZ demonstrated initial hyper-activation of the VLPFC and SMA activation that was not sustained in later regulatory phases. Response profiles in the inferior occipital gyrus in SZ showed abnormal activation in the later phases of regulation. BD-patients showed general blunted responsivity in these regions.
conclusionsThese results suggest that ER-disturbances in SZ are characterized by an inefficient initialization and failure to sustain regulatory control, whereas in BD, a failure to recruit regulatory resources may represent initial deficits in formulating adequate representations of the regulatory needs. This may help to further understand how ER-disturbances give rise to symptomatology of BD and SZ.
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