Evidence map›Paper›PMID 30772950›Full record

ReviewJournal of cellular and molecular medicine2019

The latest progress on miR-374 and its functional implications in physiological and pathological processes.

Hongjun Bian, Yi Zhou, Dawei Zhou, Yongsheng Zhang, Deya Shang, Jianni Qi

Open access · goldAbstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 72 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hongjun BianShandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Yi ZhouShandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Dawei ZhouShandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Yongsheng ZhangShandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Deya ShangShandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China.
Jianni QiShandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China.ORCID 0000-0002-9512-7762
Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-coding RNAs (ncRNAs) have been emerging players in cell development, differentiation, proliferation and apoptosis. Based on their differences in length and structure, they are subdivided into several categories including long non-coding RNAs (lncRNAs >200nt), stable non-coding RNAs (60-300nt), microRNAs (miRs or miRNAs, 18-24nt), circular RNAs, piwi-interacting RNAs (26-31nt) and small interfering RNAs (about 21nt). Therein, miRNAs not only directly regulate gene expression through pairing of nucleotide bases between the miRNA sequence and a specific mRNA that leads to the translational repression or degradation of the target mRNA, but also indirectly affect the function of downstream genes through interactions with lncRNAs and circRNAs. The latest studies have highlighted their importance in physiological and pathological processes. MiR-374 family member are located at the X-chromosome inactivation center. In recent years, numerous researches have uncovered that miR-374 family members play an indispensable regulatory role, such as in reproductive disorders, cell growth and differentiation, calcium handling in the kidney, various cancers and epilepsy. In this review, we mainly focus on the role of miR-374 family members in multiple physiological and pathological processes. More specifically, we also summarize their promising potential as novel prognostic biomarkers and therapeutic targets from bench to bedside.

Indexed as

ApoptosisBiomarkers, TumorCell ProliferationEpilepsyGene Expression RegulationGenes, X-LinkedHumansMicroRNAsNeoplasmsRNA, CircularRNA, Long NoncodingX Chromosome InactivationBiomarkers, TumorMicroRNAsMIRN374 microRNA 374, humanRNA, CircularRNA, Long Noncodingcalcium handleepilepsymiR-374ncRNAtumorigenesis

Identifiers

PMID30772950
PMCPMC6484333
OpenAlexW2917743351

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.