Trial reportBMJ open2019
Therapist-guided and parent-guided internet-delivered behaviour therapy for paediatric Tourette's disorder: a pilot randomised controlled trial with long-term follow-up.
Trial report in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 54 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Internet-based Behaviour Therapy for Tourette's Disorder and Chronic Tic Disorder: A Feasibility Study
Clinical and Cost-effectiveness of Internet-delivered Behaviour Therapy for Children and Adolescents With Tourette's Disorder: a Single-blind Randomised Controlled Trial
Randomized Clinical Study Evaluating the Treatment Outcome of Combined Virtual Tic Training in Children and Adolescents With a Chronic Tic Disorder
Who cites it
54 citing papers in PubMed, 3 syntheses or guidelines pooled it, 108 citations in OpenAlex.
- Digital psychological interventions in youth with neurological disorders: a systematic review.Journal of pediatric psychology · 2026Pooled it
- Digitally enabled therapy for chronic tic disorders and Tourette Syndrome: a systematic review and economic evaluation.Health technology assessment (Winchester, England) · 2026Pooled it
- Emerging therapeutic approaches for Tourette syndrome and other tic disorders - a systematic review of current clinical trials.European child & adolescent psychiatry · 2025Pooled it
- Therapist-guided, mobile app-assisted behavioural treatment for children and adolescents with chronic tic disorders: a pilot randomised controlled trial.European child & adolescent psychiatry · 2026Trial
- Online Transdiagnostic Emotion Regulation Treatment for Adolescents With Mental Health Problems: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Internet-Delivered Exposure and Response Prevention for Pediatric Tourette Syndrome: 12-Month Follow-Up of a Randomized Clinical Trial.JAMA network open · 2024Trial
- Online remote behavioural intervention for tics in 9- to 17-year-olds: the ORBIT RCT with embedded process and economic evaluation.Health technology assessment (Winchester, England) · 2023Trial
- Therapist-Supported Internet-Delivered Exposure and Response Prevention for Children and Adolescents With Tourette Syndrome: A Randomized Clinical Trial.JAMA network open · 2022Trial
- Internet-based guided self-help comprehensive behavioral intervention for tics (ICBIT) for youth with tic disorders: a feasibility and effectiveness study with 6 month-follow-up.European child & adolescent psychiatry · 2022Trial
- Therapist-supported online remote behavioural intervention for tics in children and adolescents in England (ORBIT): a multicentre, parallel group, single-blind, randomised controlled trial.The lancet. Psychiatry · 2021Trial
- Fidelity of Delivery and Contextual Factors Influencing Children's Level of Engagement: Process Evaluation of the Online Remote Behavioral Intervention for Tics Trial.Journal of medical Internet research · 2021Trial
- Trial
- Tourette syndrome.Nature reviews. Disease primers · 2026Review
- Article
- Digital-Supported Delivery of Behavioural Therapy for Patients with Tic Disorders: A Narrative Review.Brain sciences · 2026Review
- Immune dysregulation in pediatric tic disorders: mechanisms, biomarkers, and therapeutic frontiers.Frontiers in immunology · 2026Review
- Meta-anlaysis of Internet-based Behavior Therapy for Tic Disorder.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025Article
- Evidence-Based Behavior Therapy for Tourette Syndrome.The Psychiatric clinics of North America · 2025Review
- Current Implementation of Digital Health in Chronic Disease Management: Scoping Review.Journal of medical Internet research · 2024Article
- Addressing co-occurring conditions in behavioural therapy for tic disorders: a review and guideline.European child & adolescent psychiatry · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveBehaviour therapy (BT) for Tourette's disorder (TD) and persistent (chronic) motor or vocal tic disorder (PTD) is rarely available. We evaluated the feasibility of adapting two existing BT protocols for TD/PTD (habit reversal training (HRT) and exposure and response prevention (ERP)) into a therapist-guided and parent-guided online self-help format.
designA pilot, single-blind, parallel group randomised controlled trial.
settingA specialist outpatient clinic in Sweden.
participantsTwenty-three young people with TD/PTD, aged 8-16.
interventionsTwo 10-week therapist-guided and parent-guided internet-delivered programmes (called BIP TIC HRT and BIP TIC ERP). OUTCOME: The primary outcome measure was the Yale Global Tic Severity Scale. Blinded evaluators rated symptoms at baseline, post-treatment and 3-month follow-up (primary endpoint). All participants were naturalistically followed up to 12 months after treatment.
resultsPatients and parents rated the interventions as highly acceptable, credible and satisfactory. While both interventions resulted in reduced tic-related impairment, parent-rated tic severity and improved quality of life, only BIP TIC ERP resulted in a significant improvement on the primary outcome measure. Within-group effect sizes and responder rates were, respectively:
conclusionsInternet-delivered BT has the potential to greatly increase access to evidence-based treatment for young people with TD/PTD. Further evaluation of the efficacy and cost-effectiveness of this treatment modality is warranted. TRIAL REGISTRATION NUMBER: NCT02864589; Pre-results.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.