Evidence map›Paper›PMID 30772698›Full record

ArticleSleep medicine2019

Impact of acute sleep restriction on cerebral glucose metabolism during recovery non-rapid eye movement sleep among individuals with primary insomnia and good sleeper controls.

Daniel B Kay, Helmet T Karim, Brant P Hasler, Jeffrey A James, Anne Germain, Martica H Hall, Peter L Franzen, Julie C Price, Eric A Nofzinger, Daniel J Buysse

Open access · greenAbstract read
In one paragraph

Article in Sleep medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Daniel B KayDepartment of Psychology, Brigham Young University, Provo, UT, USA. Electronic address: daniel_kay@byu.edu.
Helmet T KarimDepartment of Psychiatry, Center for Sleep and Circadian Science, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Brant P HaslerDepartment of Psychiatry, Center for Sleep and Circadian Science, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Jeffrey A JamesDepartment of Radiology, University of Pittsburgh, Pittsburgh, PA, USA.
Anne GermainDepartment of Psychiatry, Center for Sleep and Circadian Science, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Martica H HallDepartment of Psychiatry, Center for Sleep and Circadian Science, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Peter L FranzenDepartment of Psychiatry, Center for Sleep and Circadian Science, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Julie C PriceDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Eric A NofzingerEbb Therapeutics Oakmont, PA, USA; Department of Psychiatry, Center for Sleep and Circadian Science, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Daniel J BuysseDepartment of Psychiatry, Center for Sleep and Circadian Science, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
University of Pittsburgh · USBrigham Young University · USEbb Therapeutics (United States) · USMassachusetts General Hospital · US

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
CLINICAL RESEARCH TRAINING IN LATE-LIFE MOOD DISORDERST32MH019986 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HOWARD J AIZENSTEIN, Carmen Andreescu · 1997 to 2026
$6.9M
Translational Research Training in Sleep MedicineT32HL082610 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Daniel J. Buysse, PETER L FRANZEN · 2007 to 2026
$5.8M
Testing a Neurobiological Model of Primary InsomniaR01MH024652 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BUYSSE, DANIEL J. · 1985 to 2011
$5.1M
UNDERSTANDING SHARED PSYCHOBIOLOGICAL PATHWAYSP50HL065112 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MATTHEWS, KAREN A · 1999 to 2003
$5.0M
EEG SLEEP STUDIES IN RELATION TO AFFECTIVE ILLNESSR37MH024652 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KUPFER, DAVID J · 1991 to 2000
$878k
Circadian misalignment and reward function: a novel pathway to substance useK01DA032557 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HASLER, BRANT P. · 2012 to 2016
$777k
NCATS NIH HHS UL1 TR001857NHLBI NIH HHS P50 HL065112NHLBI NIH HHS T32 HL082610NIDA NIH HHS K01 DA032557NIMH NIH HHS R01 MH024652NIMH NIH HHS R37 MH024652NIMH NIH HHS T32 MH019986
6 · The paper itself

Abstract

backgroundRestricting time in bed improves insomnia symptoms, but the neural mechanisms for this effect are unknown. Total and partial acute sleep restriction may be useful paradigms for elucidating these effects. We examined the impact of acute sleep restriction on cerebral glucose metabolism during non-rapid eye movement (NREM) sleep in individuals with primary insomnia (n = 17) and good sleep (n = 19).

methodsParticipants underwent [

resultsRelative rCMR

conclusionIndividuals with insomnia and good sleepers showed similar relative rCMR

Indexed as

AdultCerebral CortexElectroencephalographyFemaleGlucoseHumansMaleMiddle AgedPolysomnographyPositron-Emission TomographyRecovery of FunctionSleep DeprivationSleep Initiation and Maintenance DisordersSleep StagesYoung AdultGlucoseFluorodeoxyglucoseNeuroimagingPositron emission tomographyPrimary insomniaQuantitative EEGSleep restriction

Identifiers

PMID30772698
PMCPMC8232888
OpenAlexW2908033335

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.