Evidence map›Paper›PMID 30772471›Full record

ArticleContemporary clinical trials2019

Design and baseline characteristics of a low-income urban cohort of children with asthma: The Asthma Action at Erie Trial.

Giselle S Mosnaim, Sally M Weinstein, Oksana Pugach, Genesis Rosales, Angkana Roy, Surrey Walton, Molly A Martin

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Contemporary clinical trials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02481986 (Asthma Action at Erie Trial), which is not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02481986 phase3completednot on this map

Asthma Action at Erie Trial

TypeinterventionalSponsorUniversity of Illinois at ChicagoRan2015 to 2021Enrolled223ConditionsAsthma, ChildrenArmsCommunity Health Worker, Certified asthma educator
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Home-based educational interventions for children with asthma.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Pooled it
  3. Improving Adherence in Urban Youth With Asthma: Role of Community Health Workers.The journal of allergy and clinical immunology. In practice · 2022
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giselle S MosnaimNorthShore University HealthSystem, University of Illinois at Chicago, United States. Electronic address: gmosnaim@northshore.org.
Sally M WeinsteinNorthShore University HealthSystem, University of Illinois at Chicago, United States.
Oksana PugachNorthShore University HealthSystem, University of Illinois at Chicago, United States.
Genesis RosalesNorthShore University HealthSystem, University of Illinois at Chicago, United States.
Angkana RoyNorthShore University HealthSystem, University of Illinois at Chicago, United States.
Surrey WaltonNorthShore University HealthSystem, University of Illinois at Chicago, United States.
Molly A MartinNorthShore University HealthSystem, University of Illinois at Chicago, United States.

Funding

The Asthma Action at Erie TrialR01HL123797 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MARTIN, MOLLY A · 2015 to 2019
$3.3M
NHLBI NIH HHS R01 HL123797
6 · The paper itself

Abstract

objectiveTo describe the methodology of a randomized controlled trial comparing the efficacy of integrated asthma community health workers (CHW) and a certified asthma educator (AE-C) to improve asthma outcomes in low-income minority children in Chicago.

methodsChild/caregiver dyads were randomized to CHW home visits or education in the clinic from an AE-C. Intervention was delivered in the first year after enrollment. Data collection occured at baseline, 6-, 12-, 18, and 24-months. The co-primary outcomes included asthma control using the Asthma Control Test/childhood Asthma Control Test (ACT/cACT) and activity limitation over the past 14 days.

resultsA total of 223 participants ages 5-16 years were randomized. The majority of children were in the 5-11 year old range (78.9%). Most caregivers (96.9%) and 44% of children were female. Approximately 85% of caregivers and children reported Hispanic ethnicity and 62.3% reported a household income of ≤ $59,000. Over half (55.7%) had uncontrolled asthma as measured by ACT/cACT; 13.9% had a normal ACT/cACT score but were uncontrolled using the Asthma Control Questionnaire and 20.2% were controlled on both measures but had received oral steroids in the past year for asthma.

conclusionThe Asthma Action at Erie Trial successfully recruited a largely Hispanic cohort of children with uncontrolled or high-risk asthma to study the differential effects of clinic-based AE-C and home-based CHW interventions. Strengths of the trial include its comparative effectivness design that integrates interventionists and intervention delivery into a clinical setting. Categorizing asthma control in community settings for research purposes presents unique challenges. CLINICAL

trial registrationUniversity of Illinois at Chicago Protocol Record R01HL123797, Asthma Action at Erie TrialClinicalTrials.gov Identifier: NCT02481986 "ClinicalTrials.gov Registration" register@clinicaltrials.gov.

Indexed as

AsthmaCommunity Health WorkersHispanic or LatinoPatient Education as TopicPovertyAdolescentAnti-Asthmatic AgentsCaregiversChicagoChildChild, PreschoolFemaleHouse CallsHumansMaleRandomized Controlled Trials as TopicAnti-Asthmatic AgentsAdherenceAsthmaCommunity health workersDisparitiesHealth outcomesPediatrics

Identifiers

PMID30772471
PMCPMC6541387

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.