ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2019
Clinical risk factors associated with multidrug-resistant tuberculosis (MDR-TB) in Mali.
Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
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Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- Global prevalence of drug-resistant tuberculosis: a systematic review and meta-analysis.Infectious diseases of poverty · 2023Pooled it
- HIV infection and multidrug resistant tuberculosis: a systematic review and meta-analysis.BMC infectious diseases · 2021Pooled it
- Key risk factors for pulmonary vs. extrapulmonary tuberculosis: a comparative study in Southwest Ethiopia.Journal of clinical tuberculosis and other mycobacterial diseases · 2026Article
- Risk factors of multi-drug-resistant tuberculosis among tuberculosis patients in Bagmati Province, Nepal: a matched case-control study.BMC infectious diseases · 2026Article
- Prevalence of drug resistant tuberculosis and its associated factors among tuberculosis patients at wolkite health center in central Ethiopia.Scientific reports · 2026Article
- Retreatment TB is a risk factor for multidrug-resistant TB among people with HIV in rural eastern Uganda: A nested case-control study.Journal of clinical tuberculosis and other mycobacterial diseases · 2025Article
- Prevalence of Multidrug-Resistant Tuberculosis and Its Association With Previous Treatment History in Adults.Cureus · 2025Article
- Risk factors associated with morbidity and unfavorable treatment outcome in drug-resistant pulmonary tuberculosis: a case-control study.Precision clinical medicine · 2025Article
- Sociodemographic determinants of multidrug-resistant tuberculosis in Lesotho: A case-control study.PLOS global public health · 2025Article
- Prediction of risk factors associated with the development of multidrug-resistant tuberculosis in patients with tuberculosis.Frontiers in public health · 2025Article
- Efficacy and safety profile of 2Pakistan journal of medical sciences · 2024Article
- Chest X-Ray Comparison Between Drug-Resistant and Drug-Sensitive Pulmonary Tuberculosis in Children.The clinical respiratory journal · 2024Article
- The clinical profile and outcomes of drug resistant tuberculosis in Central Province of Zambia.BMC infectious diseases · 2024Review
- Global prevalence and burden of multidrug-resistant tuberculosis from 1990 to 2019.BMC infectious diseases · 2024Article
- Determinants of drug-resistant tuberculosis in Hunan province, China: a case-control study.BMC infectious diseases · 2024Article
- Epidemiology of multi-drug resistant Tuberculosis in the western region of Kenya.AIMS microbiology · 2024Article
- Tuberculosis multirresistente en Colombia, 2013-2018: estudio de casos y controlesBiomedica : revista del Instituto Nacional de Salud · 2023Article
- Assessment of risk factors associated with multi-drug resistant tuberculosis (MDR-TB) in Gulu regional referral hospital.African health sciences · 2023Article
- Radiomics analysis of lung CT for multidrug resistance prediction in active tuberculosis: a multicentre study.European radiology · 2023Article
- Characteristics of Previous Tuberculosis Treatment History in Patients with Treatment Failure and the Impact on Acquired Drug-Resistant Tuberculosis.Antibiotics (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
28 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundMDR-TB is a major threat to global TB control. In 2015, 580,000 were treated for MDR-TB worldwide. The worldwide roll-out of GeneXpert MTB/RIF
methodsWe performed a cross-sectional study of 214 patients with presumed MDR-TB admitted to University of Bamako Teaching Hospital, Point-G between 2007 and 2016. We calculated crude and adjusted odds ratios for MDR-TB disease diagnosis using SPSS.
resultsWe found that age ≤40years (OR=2.56. 95% CI: 1.44-4.55), two courses of prior TB treatment (OR=3.25, 95% CI: 1.44-7.30), TB treatment failure (OR=3.82, 95% CI 1.82-7.79), sputum microscopy with 3+ bacilli load (OR=1.98, 95% CI: 1.13-3.48) and a history of contact with a TB patient (OR=2.48, 95% CI: 1.11-5.50) were significantly associated with confirmation of MDR-TB disease. HIV was not a risk factor for MDR-TB (aOR=0.88, 95% CI: 0.34-1.94).
conclusionWe identified several risk factors that could be used to identify MDR-TB suspects and prioritize them for laboratory confirmation. Prospective studies are needed to understand factors associated with TB incidence and clinical outcomes of TB treatment and disease.
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