Evidence map›Paper›PMID 30772349›Full record

ArticleAmerican journal of ophthalmology2019

Intraocular Oxygen and Antioxidant Status: New Insights on the Effect of Vitrectomy and Glaucoma Pathogenesis.

Carla J Siegfried, Ying-Bo Shui

Open access · greenAbstract read
In one paragraph

Article in American journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 70 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Tissue-Specific Antioxidant Capacity in Primary Open-Angle Glaucoma Patients.Investigative ophthalmology & visual science · 2026
    Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. In Vivo Assessment of an Antioxidant Hydrogel Vitreous Substitute.Journal of biomedical materials research. Part A · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Carla J SiegfriedDepartment of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, Missouri. Electronic address: siegfried@wustl.edu.
Ying-Bo ShuiDepartment of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, Missouri.
Washington University in St. Louis · US

Funding

WASHINGTON UNIVERSITY CENTER VISION RESEARCHP30EY002687 · NEI · WASHINGTON UNIVERSITY · PI Philip Raymond Williams · 1985 to 2026
$18.4M
Control by Oxygen of Lens Metabolism and Cataract FormationR01EY015863 · NEI · WASHINGTON UNIVERSITY · PI BEEBE, DAVID CY · 2006 to 2009
$2.1M
Ocular Oxygen Metabolism and the Etiology of Open Angle GlaucomaR01EY021515 · NEI · WASHINGTON UNIVERSITY · PI SIEGFRIED, CARLA J · 2011 to 2014
$2.1M
NEI NIH HHS P30 EY002687NEI NIH HHS R01 EY015863NEI NIH HHS R01 EY021515
6 · The paper itself

Abstract

purposeThe purpose of this study was to investigate correlations of partial pressure of oxygen (pO

methodsThis prospective, cross-sectional study stratified patients (n = 288 eyes) by lens and vitreous status and the presence of primary open-angle glaucoma for statistical analyses. Intraocular pO

resultsFollowing prior pars plana vitrectomy, pO

conclusionsIncreased pO

Indexed as

Visual AcuityAgedAnterior ChamberAntioxidantsBiomarkersCross-Sectional StudiesFemaleFollow-Up StudiesGlaucoma, Open-AngleHumansIntraocular PressureMaleMiddle AgedOxygenProspective StudiesVitrectomyAntioxidantsBiomarkersOxygen

Identifiers

PMID30772349
PMCPMC6612589
OpenAlexW2913089581

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.