Evidence map›Paper›PMID 30771812›Full record

ReviewClinics in perinatology2019

Epidemiology of Necrotizing Enterocolitis: New Considerations Regarding the Influence of Red Blood Cell Transfusions and Anemia.

Vivek Saroha, Cassandra D Josephson, Ravi Mangal Patel

Abstract readReview
In one paragraph

Review in Clinics in perinatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Tight junction proteins and intestinal health in preterm infants.Journal of neonatal-perinatal medicine · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Stored RBC transfusions leads to the systemic inflammatory response syndrome in anemic murine neonates.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
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  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Vivek SarohaDivision of Neonatal-Perinatal Medicine, Department of Pediatrics, Emory University School of Medicine, Children's Healthcare of Atlanta, 2015 Uppergate Drive Northeast, 3rd Floor, Atlanta, GA 30322, USA.
Cassandra D JosephsonCenter for Transfusion and Cellular Therapies, Department of Pathology and Laboratory Medicine, Emory University School of Medicine, 101 Woodruff Circle, Atlanta, GA 30322, USA; Department of Pediatrics, Emory University School of Medicine, 101 Woodruff Circle, Atlanta, GA 30322, USA.
Ravi Mangal PatelDivision of Neonatal-Perinatal Medicine, Department of Pediatrics, Emory University School of Medicine, Children's Healthcare of Atlanta, 2015 Uppergate Drive Northeast, 3rd Floor, Atlanta, GA 30322, USA. Electronic address: rmpatel@emory.edu.
Children's Healthcare of Atlanta · USEmory University · US

Funding

THE RoLE OF NEONATAL ANEMIA IN LEARNING AND MEMORYP01HL046925 · NHLBI · UNIVERSITY OF IOWA · PI GEORGIEFF, MICHAEL K. · 1992 to 2022
$34.3M
Serious Hazards of Transfusion & Cellular Therapies: Mechanisms and InterventionP01HL086773 · NHLBI · EMORY UNIVERSITY · PI JONES, DEAN PAUL · 2008 to 2019
$17.9M
Red Cell Transfusion, Severe Anemia and Necrotizing EnterocolitisK23HL128942 · NHLBI · EMORY UNIVERSITY · PI PATEL, RAVI MANGAL · 2016 to 2019
$665k
NHLBI NIH HHS K23 HL128942NHLBI NIH HHS P01 HL046925NHLBI NIH HHS P01 HL086773
6 · The paper itself

Abstract

This article summarizes available evidence on the relationship between red blood cell transfusion and anemia, and necrotizing enterocolitis (NEC). We review recent studies that highlight the uncertainty of the effect of red blood cell transfusion on NEC and the potential role of anemia. We also discuss potential pathophysiologic effects of both red blood cell transfusion and anemia and highlight strategies to prevent anemia and red blood cell transfusion. We also discuss ongoing randomized trials that are likely to provide important new evidence to guide red blood cell transfusion practices.

Indexed as

AnemiaConstrictionEnterocolitis, NecrotizingErythrocyte TransfusionHumansInfant, NewbornInfant, PrematureRisk FactorsUmbilical CordBloodInfantMorbidityNeonateOxygenationPreterm

Identifiers

PMID30771812
PMCPMC6383803
OpenAlexW2903903427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.