Evidence map›Paper›PMID 30771463›Full record

ArticleExperimental gerontology2019

Objective physical activity and physical performance in middle-aged and older adults.

Nicole L Spartano, Asya Lyass, Martin G Larson, Tuyen Tran, Charlotte Andersson, Susan J Blease, Dale W Esliger, Ramachandran S Vasan, Joanne M Murabito

Open access · greenAbstract read
In one paragraph

Article in Experimental gerontology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 3 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 3 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Pooled it
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  4. Association of Physical Activity and Gait Speed: Does Context Matter?American journal of lifestyle medicine · 2026
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  9. Body composition and functional capacity as determinants of physical activity in middle-aged and older adults: a cross-sectional analysis.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Nicole L SpartanoSection of Endocrinology, Diabetes, Nutrition, and Weight Management, Boston University School of Medicine, Boston, MA, USA; Framingham Heart Study, Framingham, MA, USA. Electronic address: Spartano@bu.edu.
Asya LyassFramingham Heart Study, Framingham, MA, USA; Department of Mathematics and Statistics, Boston University, Boston, MA, USA.
Martin G LarsonFramingham Heart Study, Framingham, MA, USA; Department of Biostatistics, Boston University, Boston, MA, USA.
Tuyen TranDepartment of Biostatistics, Boston University, Boston, MA, USA.
Charlotte AnderssonFramingham Heart Study, Framingham, MA, USA; Department of Cardiology, Herlev and Gentofte Hospital, Gentofte, Denmark.
Susan J BleaseFramingham Heart Study, Framingham, MA, USA.
Dale W EsligerSchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK.
Ramachandran S VasanFramingham Heart Study, Framingham, MA, USA; Sections of Preventive Medicine and Epidemiology, and Cardiovascular Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
Joanne M MurabitoFramingham Heart Study, Framingham, MA, USA; Department of General Internal Medicine, Boston University School of Medicine, Boston, MA, USA.
Boston University · USGentofte Hospital · DKLoughborough University · GB

Funding

Proteomic Profiling of Precise Exercise Pathophenotypes Across the HFpEF SpectrumR01HL131029 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI Gregory Dyer Lewis, Matthew G. Nayor · 2016 to 2026
$7.7M
Physical Activity, Cardiometabolic Risk, and Target-Organ Damage in Older AdultsR01AG047645 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI RAMACHANDRAN, VASAN S · 2014 to 2015
$661k
Novel multi-omics approach to the biology of healthy aging: Framingham StudyR56AG029451 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LUNETTA, KATHRYN L, MURABITO, JOANNE M · 2015 to 2015
$474k
THE FRAMINGHAM HEART STUDY-N01HC25195-268025195-268025195N01HC025195 · HC · TRUSTEES OF BOSTON UNIVERSITY · PI WOLF, PHILIP A · 2002 to 2006
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NHLBI NIH HHS HHSN268201500001CNHLBI NIH HHS HHSN268201500001INHLBI NIH HHS N01 HC025195NHLBI NIH HHS R01 HL131029NIA NIH HHS R01 AG047645NIA NIH HHS R56 AG029451
6 · The paper itself

Abstract

backgroundOlder adults may have difficulty meeting the Physical Activity (PA) Guidelines. A favorable balance between PA and sedentary time (SED) is an important determinant of physical performance in older adults. Our objective was to explore associations of PA/SED with physical performance across mid-older age in adults without overt mobility disability.

methodsFramingham Offspring Study participants free of mobility disability with accelerometry and physical performance data (gait speed, chair stand time, and handgrip strength), were studied in cross-sectional analysis (n = 1352). We regressed physical performance on PA level, measured using steps, moderate to vigorous (MV)PA and SED. We stratified by age groups, adjusted for covariates, and modelled MVPA and SED separately and together as predictors.

resultsOnly 38% of adults 50-64 years and 15% of adults ≥75 years met the PA Guidelines (i.e., 150 min MVPA per week). Individuals achieving at least 5 min/day of MVPA had 0.062 ± 0.013 m/s greater gait speed and better chair stands and handgrip strength (in women) than those with <5 min/day of MVPA (p < 0.01) across mid-older age. SED was associated with poorer performance on gait speed and chair stand tests, but results were not significant after adjusting for MVPA (p > 0.05). For adults ≥75 years, every 5000 more steps/day related to ~0.045 m/s greater gait speed (p = 0.006).

conclusionOur cross-sectional study demonstrated that, across mid-older adulthood, MVPA related to better physical performance, but in adults ≥75 years, total steps walked associated with better gait speed. These data warrant future research on the impact of PA on physical performance and health outcomes in older age.

Indexed as

ExercisePhysical Functional PerformanceAccelerometryAgedAged, 80 and overCross-Sectional StudiesFemaleGeriatric AssessmentHand StrengthHumansLinear ModelsMaleMiddle AgedSedentary BehaviorWalking SpeedAccelerometryEpidemiologyGait speedPhysical functionSedentary

Identifiers

PMID30771463
PMCPMC9728559
OpenAlexW2912424376

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.