Evidence map›Paper›PMID 30771231›Full record

ArticleThe International journal of eating disorders2019

Comparisons of bone density and body composition among adolescents with anorexia nervosa and atypical anorexia nervosa.

Jason M Nagata, Jennifer L Carlson, Neville H Golden, Jin Long, Stuart B Murray, Rebecka Peebles

Abstract read
In one paragraph

Article in The International journal of eating disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jason M NagataDepartment of Pediatrics, University of California, San Francisco, California.ORCID 0000-0002-6541-0604
Jennifer L CarlsonDepartment of Pediatrics, Stanford University School of Medicine, Palo Alto, California.
Neville H GoldenDepartment of Pediatrics, Stanford University School of Medicine, Palo Alto, California.
Jin LongDepartment of Pediatrics, Stanford University School of Medicine, Palo Alto, California.
Stuart B MurrayDepartment of Psychiatry, University of California, San Francisco, California.ORCID 0000-0002-5588-2915
Rebecka PeeblesDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.ORCID 0000-0001-9360-8434

Funding

Pediatric Scientist Development Program (PSDP) [K12]K12HD000850 · NICHD · YALE UNIVERSITY · PI Sallie R. Permar · 1987 to 2026
$44.1M
Fear Conditioning and Fear Extinction in Anorexia NervosaK23MH115184 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MURRAY, STUART B · 2017 to 2021
$990k
Weight gain and functional body composition in adolescents with anorexia nervosaK23DK100558 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI PEEBLES, REBECKA · 2015 to 2019
$900k
Eunice Kennedy Shriver National Institute of Child Health and Human Development 5R01HD08216602NICHD NIH HHS K12 HD000850NIDDK NIH HHS K23 DK100558NIDDK NIH HHS K23DK100558NIH HHS 5R01HD08216602NIH HHS K23DK100558NIH HHS K23 MH115184NIMH NIH HHS K23 MH115184
6 · The paper itself

Abstract

objectiveTo compare bone mineral density (BMD) and body composition among adolescents: (a) with atypical anorexia nervosa (AAN) versus anorexia nervosa (AN) and (b) those with and without a prior history of overweight.

methodElectronic medical records of patients 9-20 years with AN or AAN who underwent dual-energy x-ray absorptiometry scans were retrospectively reviewed and analyzed.

resultsA total of 286 adolescents with AN or AAN were included. In linear regression models, AAN was associated with greater Z-scores in whole body bone mineral content (BMC, B = 0.88, p < 0.001), lumbar spine BMD (B = 0.79, p = 0.002), femoral neck BMD (B = 0.670, p = 0.009); fat mass index (B = 1.33, p = 0.003), and lean body mass index (LBMI, B = 1.10, p < 0.001) compared to AN, adjusting for age, sex, and duration of illness. A prior overweight history was associated with greater Z-scores in whole body BMC; lumbar spine BMD, total hip BMD, femoral neck BMD, and LBMI. DISCUSSION: Adolescents with AAN had higher BMD Z-scores than adolescents with AN; adolescents with a prior overweight history had greater BMD Z-scores than adolescents without a prior overweight history. These findings may inform clinical guidelines for the medical management of AAN.

Indexed as

Absorptiometry, PhotonAdolescentAdultAnorexia NervosaBody CompositionBone DensityChildFemaleHumansMaleRetrospective StudiesYoung Adultanorexia nervosaatypical anorexia nervosabody compositionbone densitybone healthdual-energy x-ray absorptiometryDXAeating disordersobesityoverweight

Identifiers

PMID30771231
PMCPMC6613651

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.