ArticleJournal of autism and developmental disorders2020
A Quantitative Sensory Testing Approach to Pain in Autism Spectrum Disorders.
Article in Journal of autism and developmental disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06659731 (Pain Perception in Autism. Study Through Quantitative Sensory Testing and Psychophysiological Correlates), which is not on this map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pain Perception in Autism. Study Through Quantitative Sensory Testing and Psychophysiological Correlates
Who cites it
29 citing papers in PubMed, 58 citations in OpenAlex.
- How the Brain Interprets Pain in Autistic People: Does Sex Matter?European journal of pain (London, England) · 2026Article
- Pain Expectation in Individuals With High Autistic Traits: Decision-Evaluation Processes and Oxytocin Modulation.Annals of the New York Academy of Sciences · 2026Article
- Plasma EAAT2 and GABA as candidate biomarkers in males with autism spectrum disorder: an exploratory case-control study with ROC analysis.Scientific reports · 2026Article
- Article
- Modifying quantitative sensory testing to investigate tactile sensory function and behavioral reactivity in children with intellectual and developmental disabilities: establishing feasibility and testing sex, autism, and self-injury effects.Journal of neurodevelopmental disorders · 2025Article
- Pain experience and perception in individuals with Snijders Blok-Campeau syndrome.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- Pain perception in autism. A study of sensory reactivity in children and adolescents with autism using quantitative sensory testing and psychophysiological correlates.Frontiers in neuroscience · 2025Article
- Involvement of sphingosine-1-phosphate receptor 1 in pain insensitivity in a BTBR mouse model of autism spectrum disorder.BMC medicine · 2024Article
- Social Determinants and Consequences of Pain: Toward Multilevel, Intersectional, and Life Course Perspectives.The journal of pain · 2024Review
- Understanding the impacts of chronic pain on autistic adolescents and effective pain management: a reflexive thematic analysis adolescent-maternal dyadic study.Journal of pediatric psychology · 2024Article
- Article
- Interoception in Autism: A Narrative Review of Behavioral and Neurobiological Data.Psychology research and behavior management · 2024Review
- Pain assessment in autism: updating the ethical and methodological challenges through a state-of-the-art review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Review
- Disturbance of skin sensation and autism spectrum disorder: A bidirectional Mendelian randomization study.Brain and behavior · 2023Article
- Headache in Individuals with Neurodevelopmental Disorders.Current pain and headache reports · 2023Review
- Autistic Traits and Empathy for Others' Pain Among the General Population: Test of the Mediating Effects of First-Hand Pain Sensitivity.Journal of autism and developmental disorders · 2023Article
- Maternal autistic traits and antenatal pain by cross-sectional analysis of the Japan Environment and Children's Study.Scientific reports · 2023Article
- Qualitative and quantitative analysis of self-reported sensory issues in individuals with neurodevelopmental disorders.Frontiers in psychiatry · 2023Article
- Modifying quantitative sensory testing to investigate behavioral reactivity in a pediatric global developmental delay sample: Relation to peripheral innervation and chronic pain outcomes.Developmental psychobiology · 2022Article
- Autism and chronic ill health: an observational study of symptoms and diagnoses of central sensitivity syndromes in autistic adults.Molecular autism · 2022Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sensory abnormalities in autism has been noted clinically, with pain insensitivity as a specified diagnostic criterion. However, there is limited research using psychophysically robust techniques. Thirteen adults with ASD and 13 matched controls completed an established quantitative sensory testing (QST) battery, supplemented with measures of pain tolerance and central modulation. The ASD group showed higher thresholds for light touch detection and mechanical pain. Notably, the ASD group had a greater range of extreme scores (the number of z-scores outside of the 95% CI > 2), dynamic mechanical allodynia and paradoxical heat sensation; phenomena not typically seen in neurotypical individuals. These data support the need for research examining central mechanisms for pain in ASD and greater consideration of individual difference.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.