Evidence map›Paper›PMID 30771073›Full record

ArticleMikrochimica acta2019

Extraction of nucleobases, nucleosides and nucleotides by employing a magnetized graphene oxide functionalized with hydrophilic phytic acid and titanium(IV) ions.

Qian Zhang, Dong-Dong Zhou, Fan Li, Yin-Zhen Wang, Feng-Qing Yang

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Qian ZhangSchool of Chemistry and Chemical Engineering, Chongqing University, Chongqing, 401331, People's Republic of China.
Dong-Dong ZhouSchool of Chemistry and Chemical Engineering, Chongqing University, Chongqing, 401331, People's Republic of China.
Fan LiSchool of Chemistry and Chemical Engineering, Chongqing University, Chongqing, 401331, People's Republic of China.
Yin-Zhen WangSchool of Chemistry and Chemical Engineering, Chongqing University, Chongqing, 401331, People's Republic of China.
Feng-Qing YangSchool of Chemistry and Chemical Engineering, Chongqing University, Chongqing, 401331, People's Republic of China. fengqingyang@cqu.edu.cn.ORCID http://orcid.org/0000-0002-9300-5710
Chongqing University · CN

Funding

National Natural Science Foundation of China 21275169
6 · The paper itself

Abstract

A magnetite@graphene oxide nanocomposite was first coated with polyethylenimine and then modified with phytic acid and titanium(IV) ions. The high loading with Ti(IV) and the good hydrophilicity of PEI and PA result in a material that can be applied to the efficient extraction of highly polar nucleobases, nucleosides and nucleotides. The physicochemical properties of the composite were investigated by scanning electron microscopy, transmission electron microscopy, energy dispersive X-ray spectroscopy, Fourier transform infrared spectroscopy, water contact angle measurements, thermogravimetric analysis, and vibrating sample magnetometry. A series of parameters that affect extraction and elution under the conditions of immobilized metal affinity chromatography (IMAC) and hydrophilic interaction liquid chromatography (HILIC) were examined. The analytes were eluted from the nanocomposites using 10 mM trisodium phosphate as the elution solution in the IMAC mode, and 50% methanol-water as elution solution in the HILIC mode. Figures of merit include (a) an intra-day precision of 0.1-1.0% in the IMAC mode; (b) an intra-day precision of 0.4%-0.8% in the HILIC mode; (c) detection limits between 1.8-2.8 ng mL

Indexed as

AdsorptionAnimalsCordycepsFerrosoferric OxideGraphiteLimit of DetectionMagnetic PhenomenaNanocompositesNucleosidesNucleotidesOxidesPhytic AcidPolyethyleneimineRabbitsShiitake MushroomsSolid Phase ExtractionFerrosoferric OxideGraphiteNucleosidesNucleotidesOxidesPhytic AcidPolyethyleneimineTitaniumHydrophilic interaction liquid chromatographyImmobilized metal ion chromatographyMagnetic solid phase extractionNucleobase-based compounds

Identifiers

PMID30771073
OpenAlexW2914422141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.