Evidence map›Paper›PMID 30771008›Full record

ArticleMikrochimica acta2019

Simultaneous voltammetric sensing of levodopa, piroxicam, ofloxacin and methocarbamol using a carbon paste electrode modified with graphite oxide and β-cyclodextrin.

Anderson Martin Santos, Ademar Wong, Fernando Campanhã Vicentini, Orlando Fatibello-Filho

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anderson Martin SantosDepartment of Chemistry, Federal University of São Carlos, Rod. Washington Luís km 235, São Carlos, SP, CEP: 13560-970, Brazil.
Ademar WongDepartment of Chemistry, Federal University of São Carlos, Rod. Washington Luís km 235, São Carlos, SP, CEP: 13560-970, Brazil.
Fernando Campanhã VicentiniCenter of Nature Sciences, Federal University of São Carlos, Rod. Lauri Simões de Barros km 12, Buri, SP, CEP: 18290-000, Brazil. fcvicentini@ufscar.br.ORCID http://orcid.org/0000-0001-6075-2579
Orlando Fatibello-FilhoDepartment of Chemistry, Federal University of São Carlos, Rod. Washington Luís km 235, São Carlos, SP, CEP: 13560-970, Brazil.
Universidade Federal de São Carlos · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico (BR) 160150/2015-9Conselho Nacional de Desenvolvimento Científico e Tecnológico (BR) 408430/2016-8
6 · The paper itself

Abstract

A carbon paste electrode (CPE) was modified with graphite oxide (GrO) and β-cyclodextrin (CD) to obtain a sensor for simultaneous voltammetric determination of levodopa (LD), piroxicam (PRX), ofloxacin (OFX) and methocarbamol (MCB). The morphology, structure and electrochemical properties of the functionalized GrO were characterized by scanning electron microscopy, energy-dispersive X-ray spectroscopy, contact angle measurements and cyclic voltammetry. Under the optimal experimental conditions, the sensor is capable of detecting LD, PRX, OFX and MCB by square wave voltammetry (SWV) at working potentials of +0.40, +0.60, +1.03 and + 1.27 V (versus Ag/AgCl), respectively. Response is linear from 1.0 to 20 μM for LD, from 1.0 to 15 μM for PRX, from 1.0 to 20 μM for OFX, and from 1.0 to 50 μM for MCB. The respective limits of detection are 65, 105, 89 and 400 nM. The method was successfully applied to the simultaneous determination of LD, PRX, OFX and MCB in (spiked) real river water and synthetic urine samples, and the results were in agreement with those obtained using a spectrophotometric method, with recoveries close to 100%. Graphical abstract Schematic presentation of a novel electroanalytical method employing a carbon paste electrode modified with graphite oxide and β-cyclodextrin for the simultaneous determination of levodopa, piroxicam, ofloxacin and methocarbamol in urine and river water samples by square wave voltammetry.

Indexed as

beta-CyclodextrinsElectrochemical TechniquesElectrodesGraphiteLevodopaLimit of DetectionMethocarbamolOfloxacinOxidesPiroxicamReproducibility of ResultsRiversbeta-CyclodextrinsbetadexGraphiteLevodopaMethocarbamolOfloxacinOxidesPiroxicamGraphite oxideNanostructured materialsRiver water analysisSimultaneous sensingUrine analysisβ-Cyclodextrin

Identifiers

PMID30771008
OpenAlexW2913202367

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.