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ArticleHypertension research : official journal of the Japanese Society of Hypertension2019

Characteristics of visit-to-visit blood pressure variability in hemodialysis patients.

Yoshifumi Amari, Satoshi Morimoto, Takeshi Iida, Takatomi Yurugi, Yasuo Oyama, Naoki Aoyama, Fumitaka Nakajima, Satoru Shimizu, Atsuhiro Ichihara

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Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Asian expert consensus on high-quality hypertension management.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Review
  2. Article
  3. Article
  4. Visit-to-visit blood pressure variability and clinical outcomes in peritoneal dialysis - based on machine learning algorithms.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yoshifumi AmariDepartment of Endocrinology and Hypertension, Tokyo Women's Medical University, Tokyo, Japan.
Satoshi MorimotoDepartment of Endocrinology and Hypertension, Tokyo Women's Medical University, Tokyo, Japan. morimoto.satoshi@twmu.ac.jp.
Takeshi IidaDepartment of Endocrinology and Hypertension, Tokyo Women's Medical University, Tokyo, Japan.
Takatomi YurugiDepartment of Nephrology, Moriguchi Keijinkai Hospital, Osaka, Japan.
Yasuo OyamaDepartment of Nephrology and Dialysis, Neyagawa Keijinkai Clinic, Osaka, Japan.
Naoki AoyamaDepartment of Nephrology and Dialysis, Moriguchi Keijinkai Clinic, Osaka, Japan.
Fumitaka NakajimaDepartment of Nephrology and Dialysis, Kadoma Keijinkai Clinic, Osaka, Japan.
Satoru ShimizuDepartment of Medical Education, Tokyo Women's Medical University, Tokyo, Japan.
Atsuhiro IchiharaDepartment of Endocrinology and Hypertension, Tokyo Women's Medical University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Visit-to-visit blood pressure variability (VVBPV) is an independent risk factor for cardiovascular morbidity and mortality in the general population. Hemodialysis (HD) patients have a poor prognosis due to an increased prevalence of cardiovascular disease. Intradialytic hypotension is associated with excess mortality, but whether VVBPV influences mortality is still unclear in HD patients. The present study aimed to investigate the characteristics of VVBPV in these patients. A total of 324 maintenance HD patients, who could be followed for 60 months, were recruited. We used variation independent of the mean (VIM) in pre-dialysis systolic blood pressure (pre-VIM-SBP) as an index of VVBPV. We investigated (1) the reproducibility of pre-VIM-SBP, (2) the relationship between pre-VIM-SBP and background factors, and (3) the association between pre-VIM-SBP and mortality. Pre-VIM-SBP showed significant reproducibility [intraclass correlation, 0.45 (P < 0.001)]. Higher pre-VIM-SBP was associated with less physical activity and worse left ventricular diastolic function. Higher pre-VIM-SBP was associated with a higher rate of cardiovascular deaths independent of other factors. These data suggest that VVBPV in HD patients is reproducible and associated with various background factors. VVBPV is independently correlated with cardiovascular mortality (hazard ratio: 1.166, 95% confidence interval: 1.030-1.320, P = 0.015). Further studies are necessary to confirm the mechanism of increased VVBPV and to clarify whether reducing VVBPV will improve the prognosis for HD patients.

Indexed as

Renal DialysisAdultAgedAged, 80 and overBlood PressureCardiovascular DiseasesFemaleHumansMaleMiddle AgedPrognosisRenal Insufficiency, ChronicReproducibility of ResultsRisk FactorsSurvival RateArteriosclerosisCardiovascular deathPrognosisReproducibilityVariation independent of the mean

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.