Evidence map›Paper›PMID 30770875›Full record

ArticleCell death and differentiation2019

In the absence of apoptosis, myeloid cells arrest when deprived of growth factor, but remain viable by consuming extracellular glucose.

Li Dong, Boris Reljic, Jen G Cheung, Elizabeth S Ng, Lisa M Lindqvist, Andrew G Elefanty, David L Vaux, Hoanh Tran

Open access · bronzeAbstract read
In one paragraph

Article in Cell death and differentiation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Li DongThe Walter and Eliza Hall Institute of Medical Research and the Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.
Boris ReljicThe Walter and Eliza Hall Institute of Medical Research and the Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.
Jen G CheungThe Walter and Eliza Hall Institute of Medical Research and the Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.
Elizabeth S NgMurdoch Childrens Research Institute, The Royal Children's Hospital, Parkville, VIC, Australia.
Lisa M LindqvistThe Walter and Eliza Hall Institute of Medical Research and the Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.ORCID http://orcid.org/0000-0002-2421-2740
Andrew G ElefantyMurdoch Childrens Research Institute, The Royal Children's Hospital, Parkville, VIC, Australia.
David L VauxThe Walter and Eliza Hall Institute of Medical Research and the Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.ORCID http://orcid.org/0000-0003-2703-1651
Hoanh TranThe Walter and Eliza Hall Institute of Medical Research and the Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia. tran.h@wehi.edu.au.ORCID http://orcid.org/0000-0002-0176-4112
The University of Melbourne · AURoyal Children's Hospital · AU

Funding

Department of Health | National Health and Medical Research Council (NHMRC) 1113133Leukemia and Lymphoma Society (Leukemia & Lymphoma Society) 7001-13
6 · The paper itself

Abstract

Withdrawal of the growth factor interleukin-3 (IL-3) from IL-3-dependent myeloid cells causes them to undergo Bax/Bak1-dependent apoptosis, whereas factor-deprived Bax

Indexed as

AnimalsApoptosisAutophagy-Related Protein 5bcl-2-Associated X Proteinbcl-2 Homologous Antagonist-Killer ProteinCell SurvivalGene Knockout TechniquesGlucoseInterleukin-3MiceMyeloid CellsAtg5 protein, mouseAutophagy-Related Protein 5Bak1 protein, mouseBax protein, mousebcl-2-Associated X Proteinbcl-2 Homologous Antagonist-Killer ProteinGlucoseInterleukin-3

Identifiers

PMID30770875
PMCPMC6748108
OpenAlexW2912088832

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.