Evidence map›Paper›PMID 30770827›Full record

ArticleNature communications2019

A functional subset of CD8

Lara M Myers, Michal Caspi Tal, Laughing Bear Torrez Dulgeroff, Aaron B Carmody, Ronald J Messer, Gunsagar Gulati, Ying Ying Yiu, Matthew M Staron, Cesar Lopez Angel, Rahul Sinha and 10 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 78 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. CD47 monoclonal antibodies differ in their capacity to induce immune response.European journal of microbiology & immunology · 2025
    Article
  6. Article
  7. Loss of NR2F6 Protects from Salmonella Typhimurium Infection.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. CD47/SIRPα axis: bridging innate and adaptive immunity.Journal for immunotherapy of cancer · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 1 country.

Lara M MyersLaboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, Hamilton, MT, 59840, USA.
Michal Caspi TalInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.ORCID http://orcid.org/0000-0003-2550-6246
Laughing Bear Torrez DulgeroffInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Aaron B CarmodyResearch Technologies Branch, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT, 59840, USA.
Ronald J MesserLaboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, Hamilton, MT, 59840, USA.
Gunsagar GulatiInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Ying Ying YiuInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Matthew M StaronResearch Technologies Branch, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT, 59840, USA.
Cesar Lopez AngelDeparment of Immunology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Rahul SinhaInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Maxim MarkovicInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Edward A PhamInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Benjamin FramDepartment of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Aijaz AhmedDepartment of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Aaron M NewmanInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.ORCID http://orcid.org/0000-0002-1857-8172
Jeffrey S GlennDepartment of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Mark M DavisDeparment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, 94305, USA.ORCID http://orcid.org/0000-0001-6868-657X
Susan M KaechDepartment of Immunobiology, Yale School of Medicine, New Haven, CT, 06520, USA.
Irving L WeissmanInstitute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.ORCID http://orcid.org/0000-0002-9077-7467
Kim J HasenkrugLaboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, Hamilton, MT, 59840, USA. khasenkrug@nih.gov.ORCID http://orcid.org/0000-0001-8523-4911
Stanford University · USRocky Mountain Research (United States) · USAbbVie (United States) · USSalk Institute for Biological Studies · US

Funding

Using a tonsil organoid system to probe conditions for the induction of protective antibody and T cell responses to influenza.U19AI057229 · NIAID · STANFORD UNIVERSITY · PI Mark Morris Davis · 2003 to 2026
$88.5M
Viral Vector Core (VVC)P30CA014195 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Ye Zheng · 1985 to 2026
$82.8M
Translational Incubator CoreU19AI109662 · NIAID · STANFORD UNIVERSITY · PI GLENN, JEFFREY S · 2014 to 2019
$28.6M
MOLECULAR &CELLULAR IMMUNOBIOLOGYT32AI007290 · NIAID · STANFORD UNIVERSITY · PI Sean Curtis Bendall, Olivia M Martinez · 1985 to 2026
$27.0M
Immunology And Pathology Of Acute Murine Leukemia Virus InfectionsZIAAI000753 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI HASENKRUG, KIM · 2009 to 2022
$8.1M
Interrogation of individual cells to identify progenitors and their nichesU01HL099999 · NHLBI · STANFORD UNIVERSITY · PI WEISSMAN, IRVING L. · 2009 to 2015
$7.8M
MOLECULAR CHARACTERIZATION OF ACUTE MYELOID LEUKEMIAR01CA086017 · NCI · STANFORD UNIVERSITY · PI WEISSMAN, IRVING L. · 2000 to 2015
$5.5M
HIV Infection in Humanized MiceZIAAI001141 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI HASENKRUG, KIM · 2011 to 2019
$4.2M
Structure-function determination of the Hepatitis C Virus negative RNA strand's 3'-terminal sequenceF30DK099017 · NIDDK · STANFORD UNIVERSITY · PI PHAM, EDWARD ANHOA · 2013 to 2015
$98k
Immunotherapy targeting the CD47-SIRPα axis to promote immune clearance of chronic infectionF32AI124558 · NIAID · STANFORD UNIVERSITY · PI TAL, MICHAL CASPI · 2016 to 2017
$83k
NCI NIH HHS P30 CA014195NCI NIH HHS R01 CA086017NHLBI NIH HHS U01 HL099999NIAID NIH HHS F32 AI124558NIAID NIH HHS T32 AI007290NIAID NIH HHS U19 AI057229NIAID NIH HHS U19 AI109662NIDDK NIH HHS F30 DK099017
6 · The paper itself

Abstract

Prolonged exposure of CD8

Indexed as

AnimalsArenaviridae InfectionsCD8-Positive T-LymphocytesFemaleGene ExpressionGene Expression ProfilingHost-Pathogen InteractionsHumansLymphocyte ActivationLymphocytic ChoriomeningitisLymphocytic choriomeningitis virusMice, Inbred C57BLMice, TransgenicReceptors, ImmunologicT-Lymphocytes, CytotoxicReceptors, ImmunologicSirpa protein, mouse

Identifiers

PMID30770827
PMCPMC6377614
OpenAlexW2911813338

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.