ArticleNature communications2019
Tear resistance of soft collagenous tissues.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed.
- From Bench to Operating Room: A Comparative Study of Tensile and Puncture Tests in Self-Assembled Constructs with Clinical Feedback.Bioengineering (Basel, Switzerland) · 2026Article
- Machine Learning Prediction of Vaginal Tissue Tears Using Finite Element Simulations Informed by Planar Biaxial Testing.Annals of biomedical engineering · 2026Article
- Compliance for Resistance: The Intrinsic Extraordinary Isotropic Anti-Fatigue Performance of Fish Bladder.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Microscopic measurement of the local deformation field establishes the mechanistic origin of the fatigue threshold for soft brittle materials.Soft matter · 2026Article
- Tough and Rapidly Relaxing Hydrogels Via Programmable Crosslink Kinetics.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Structural Motifs in Soft Fibrous Tissues: Revealing Structure-Mechanics Relationships in Deformation and Tear Resistance for Biomimetic Material Design.Advanced healthcare materials · 2025Review
- Why are soft collagenous tissues so tough?Science advances · 2025Article
- Prediction of tissue rupture from percolation of local strain heterogeneities for diagnostics.Communications medicine · 2025Article
- A tough soft-hard interface in the human knee joint driven by multiscale toughening mechanisms.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- A multiscale discrete fiber model of failure in heterogeneous tissues: Applications to remodeled cerebral aneurysms.Journal of biomechanics · 2025Article
- Being thin-skinned can still reduce damage from dynamic puncture.Journal of the Royal Society, Interface · 2024Article
- Curving expectations: The minimal impact of structural curvature in biological puncture mechanics.Science advances · 2024Article
- Nano cells from fruit bunch residue: Nestling nanotechnology within the circular oil palm milling residue management.Heliyon · 2024Article
- Article
- Cracks in tensile-contracting and tensile-dilating poroelastic materials.International journal of solids and structures · 2024Article
- Crosslinking degree variations enable programming and controlling soft fracture via sideways cracking.npj computational materials · 2024Article
- Flaw-insensitive fatigue resistance of chemically fixed collagenous soft tissues.Science advances · 2023Article
- Orientation-dependent indentation reveals the crosslink-mediated deformation mechanisms of collagen fibrils.Acta biomaterialia · 2023Article
- Energy release rate for cracks in hydrogels undergoing finite deformations.Journal of the mechanics and physics of solids · 2022Article
- Risky interpretations across the length scales: continuum vs. discrete models for soft tissue mechanobiology.Biomechanics and modeling in mechanobiology · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fracture toughness characterizes the ability of a material to maintain a certain level of strength despite the presence of a macroscopic crack. Understanding this tolerance for defects in soft collagenous tissues (SCT) has high relevance for assessing the risks of fracture after cutting, perforation or suturing. Here we investigate the peculiar toughening mechanisms of SCT through dedicated experiments and multi-scale simulations, showing that classical concepts of fracture mechanics are inadequate to quantify and explain the high defect tolerance of these materials. Our results demonstrate that SCT strength is only modestly reduced by defects as large as several millimeters. This defect tolerance is achieved despite a very narrow process zone at the crack tip and even for a network of brittle fibrils. The fracture mechanics concept of tearing energy fails in predicting failure at such defects, and its magnitude is shown to depend on the chemical potential of the liquid environment.
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