ArticleCell death & disease2019
MKK3 modulates JNK-dependent cell migration and invasion.
Article in Cell death & disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 43 citations in OpenAlex.
- Review
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- Dapagliflozin ameliorates intestinal stem cell aging by regulating the MAPK signaling pathway inFrontiers in cell and developmental biology · 2025Article
- Effect and underlying mechanism of a photochemotherapy dual-function nanodrug delivery system for head and neck squamous cell carcinoma.Journal of translational medicine · 2024Article
- Experience-dependent glial pruning of synaptic glomeruli during the critical period.Scientific reports · 2024Article
- Comprehensive bioinformatic analysis of the expression and prognostic significance of TSC22D domain family genes in adult acute myeloid leukemia.BMC medical genomics · 2023Article
- DNMT1 Mediated CAHM Repression Promotes Glioma Invasion via SPAK/JNK Pathway.Cellular and molecular neurobiology · 2022Article
- Epidermal growth factor receptor cascade prioritizes the maximization of signal transduction.Scientific reports · 2022Article
- The CRTC-CREB axis functions as a transcriptional sensor to protect against proteotoxic stress in Drosophila.Cell death & disease · 2022Article
- dGLYAT modulates Gadd45-mediated JNK activation and cell invasion.Cell division · 2022Article
- The Role of PKC-MAPK Signalling Pathways in the Development of Hyperglycemia-Induced Cardiovascular Complications.International journal of molecular sciences · 2022Review
- Article
- Usp8 promotes tumor cell migration through activating the JNK pathway.Cell death & disease · 2022Article
- Review
- Stellettin B Isolated fromInternational journal of cell biology · 2022Article
- Discovery of the first chemical tools to regulate MKK3-mediated MYC activation in cancer.Bioorganic & medicinal chemistry · 2021Article
- Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The c-Jun N-terminal kinase (JNK) pathway plays essential roles in regulating a variety of physiological processes including cell migration and invasion. To identify critical factors that regulate JNK-dependent cell migration, we carried out a genetic screen in Drosophila based on the loss-of-cell polarity-triggered cell migration in the wing epithelia, and identified MKK3 licorne (lic) as an essential regulator of JNK-mediated cell migration and invasion. We found that loss of lic suppressed ptc > scrib-IR or ptc > Egr triggered cell migration in the wing epithelia, and Ras
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