Evidence map›Paper›PMID 30770743›Full record

ArticleBMC endocrine disorders2019

Performance of HbA1c versus oral glucose tolerance test (OGTT) as a screening tool to diagnose dysglycemic status in high-risk Thai patients.

Yotsapon Thewjitcharoen, Amia Jones Elizabeth, Siriwan Butadej, Soontaree Nakasatien, Phawinpon Chotwanvirat, Ekgaluck Wanothayaroj, Sirinate Krittiyawong, Tinapa Himathongkam, Thep Himathongkam

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMC endocrine disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
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  14. Continuous Glucose Monitoring for Prediabetes: What Are the Best Metrics?Journal of diabetes science and technology · 2024
    Review
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  17. Hyperinsulinemia: an early biomarker of metabolic dysfunction.Frontiers in clinical diabetes and healthcare · 2023
    Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yotsapon ThewjitcharoenDiabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand. kamijoa@hotmail.com.ORCID http://orcid.org/0000-0002-2317-4041
Amia Jones ElizabethDiabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand.
Siriwan ButadejDiabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand.
Soontaree NakasatienDiabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand.
Phawinpon ChotwanviratDiabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand.
Ekgaluck WanothayarojDiabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand.
Sirinate KrittiyawongDiabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand.
Tinapa HimathongkamDiabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand.
Thep HimathongkamDiabetes and Thyroid Center, Theptarin Hospital, Bangkok, Thailand.
Bangkok Hospital · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDysglycemic status defined by prediabetes and diabetes is known to be related with future risk of diabetic complications and cardiovascular diseases. Herein, we aimed to determine the diagnostic accuracy of glycated hemoglobin (HbA1c) when compared with oral glucose tolerance test (OGTT) as a reference test in identifying dysglycemic status among high-risk Thai patients receiving care in an out-patient setting.

methodsAn 11-year retrospective cross-sectional study of high-risk Thai patients who underwent OGTT during 2007-2017 was analysed. The OGTT was used as a reference test to identify subjects of dysglycemic status. The diagnostic accuracy of HbA1c and the agreement between HbA1c and OGTT were examined. Validated Thai diabetes risk score, Thai cardiovascular risk score (Thai CV risk score), and visceral fat area (VFA) were also compared in each glycemic status from OGTT as surrogate markers for future diabetes and cardiovascular diseases.

resultsA total of 512 subjects (females 60.5%, mean age of 50.3 ± 12.7 years, BMI of 26.5 ± 4.6 kg/m

conclusionsDespite the practicality and validity of HbA1c as a diagnostic test, our study suggested that HbA1c as a screening tool for diabetes in high-risk Thai patients is much inferior to OGTT. With limitations of HbA1c, physicians should continue to advocate OGTT as a screening tool for the identification of dysglycemic status in high-risk Thai patients.

Indexed as

BiomarkersBlood GlucoseCross-Sectional StudiesDiabetes MellitusFemaleFollow-Up StudiesGlucose IntoleranceGlucose Tolerance TestGlycated HemoglobinHumansMaleMass ScreeningMiddle AgedPrediabetic StatePrognosisRetrospective StudiesBiomarkersBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanDiagnostic accuracyDysglycemiaHbA1cOGTTPerformance

Identifiers

PMID30770743
PMCPMC6377733
OpenAlexW2917647459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.