ArticleBMC genomics2019
Polygenic and sex specific architecture for two maturation traits in farmed Atlantic salmon.
Article in BMC genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Genetic deletion of miR-200a/200b increases growth and feed conversion efficiency in yellow catfish.Science China. Life sciences · 2026Article
- GWAS on early sexual maturation across freshwater and seawater environments in domesticated Lochy strain of Atlantic salmon.Genetics, selection, evolution : GSE · 2026Article
- Genomic Signatures of Domestication in European Seabass (Ecology and evolution · 2024Article
- Optimizing reproductive performance in pangasius catfish broodstock: A review of dietary and molecular strategies.Veterinary and animal science · 2024Review
- Variable parallelism in the genomic basis of age at maturity across spatial scales in Atlantic Salmon.Ecology and evolution · 2024Article
- FishSNP: a high quality cross-species SNP database of fishes.Scientific data · 2024Article
- Investigating structural variant, indel and single nucleotide polymorphism differentiation between locally adapted Atlantic salmon populations.Evolutionary applications · 2024Article
- Investigating the role of genetic variation inEcology and evolution · 2023Article
- Atlantic salmon (Conservation physiology · 2023Article
- Leveraging transcriptome and epigenome landscapes to infer regulatory networks during the onset of sexual maturation.BMC genomics · 2022Article
- Detection of selection signatures in farmed coho salmon (Oncorhynchus kisutch) using dense genome-wide information.Scientific reports · 2021Article
- Genomic Selection and Genome-wide Association Study for Feed-Efficiency Traits in a Farmed Nile Tilapia (Frontiers in genetics · 2021Article
- Beyond large-effect loci: large-scale GWAS reveals a mixed large-effect and polygenic architecture for age at maturity of Atlantic salmon.Genetics, selection, evolution : GSE · 2020Article
- Transcription Profiles of Age-at-Maturity-Associated Genes Suggest Cell Fate Commitment Regulation as a Key Factor in the Atlantic Salmon Maturation Process.G3 (Bethesda, Md.) · 2020Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA key developmental transformation in the life of all vertebrates is the transition to sexual maturity, whereby individuals are capable of reproducing for the first time. In the farming of Atlantic salmon, early maturation prior to harvest size has serious negative production impacts.
resultsWe report genome wide association studies (GWAS) using fish measured for sexual maturation in freshwater or the marine environment. Genotypic data from a custom 50 K single nucleotide polymorphism (SNP) array was used to identify 13 significantly associated SNP for freshwater maturation with the most strongly associated on chromosomes 10 and 11. A higher number of associations (48) were detected for marine maturation, and the two peak loci were found to be the same for both traits. The number and broad distribution of GWAS hits confirmed a highly polygenetic nature, and GWAS performed separately within males and females revealed sex specific genetic behaviour for loci co-located with positional candidate genes phosphatidylinositol-binding clathrin assembly protein-like (picalm) and membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (magi2).
conclusionsThe results extend earlier work and have implications for future applied breeding strategies to delay maturation in this important aquaculture species.
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