ReviewRheumatology (Oxford, England)2021
Comorbidities (excluding lymphoma) in Sjögren's syndrome.
Review in Rheumatology (Oxford, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 43 citations in OpenAlex.
- Fatigue in Sjögren's Disease - Integrating Biomedical and Psychosocial Aspects: A Narrative Review.Rheumatology and therapy · 2026Review
- Investigation of Core Stabilization Strength and Pelvic Floor Functions in Patients with Primary Sjögren's Syndrome: A Case-Control Study.International urogynecology journal · 2026Observational
- A multi-criterion feature integration framework for accurate diagnosis of Sjögren's disease using routine laboratory tests.NPJ digital medicine · 2025Article
- [Effect of aquaporin 5 on TLR4/MyD88/NF-κB signaling pathway in Sjögren syndrome rats].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025Article
- Prevalence of solid tumors and lymphoma in the Brazilian Sjögren's Disease Registry (BRAS): an important concern for clinical practice.Advances in rheumatology (London, England) · 2025Article
- Exploring the role of alternative splicing in the pathogenesis of Sjögren's syndrome: identification of novel isoforms associated with salivary gland immune infiltration.Genes & genomics · 2025Article
- Higher Mortality Risk From Ovarian Carcinomas, Small Bowel Neoplasms, and B-Cell and Mucosa-Associated Lymphoid Tissue Lymphomas in Sjögren Syndrome Patients.Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2025Article
- Evaluation of the Incidence of Malignancy in Sjögren's Syndrome: A Single-Center Study From Turkey.Cureus · 2025Article
- Clinical characteristics and risk factors for primary SjögrenZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023Article
- Hospitalizations for infections in primary Sjögren's syndrome patients: a nationwide incidence study.Annals of medicine · 2022Article
- Association between a History of herpes zoster and the risk of Sjögren's syndrome: a nationwide, population-based, case-control study.BMJ open · 2022Article
- The risk of cancer in patients with primary Sjögren syndrome: a single-center study from Turkey.Turkish journal of medical sciences · 2022Article
- Hospitalization Risks for Neurological Disorders in Primary Sjögren's Syndrome Patients.Journal of clinical medicine · 2022Article
- Comorbidities in the UK Primary Sjögren's Syndrome Registry.Frontiers in immunology · 2022Article
- Sex differences in comorbidities associated with Sjögren's disease.Frontiers in medicine · 2022Article
- Primary Sjögren's syndrome as independent risk factor for subclinical atherosclerosis.European journal of rheumatology · 2022Article
- Comment on: Comorbidities (excluding lymphoma) in Sjögren's syndrome. Reply.Rheumatology (Oxford, England) · 2021Article
- Sex Differences in Otolaryngology: Focus on the Emerging Role of Estrogens in Inflammatory and Pro-Resolving Responses.International journal of molecular sciences · 2021Review
- P2YArchives of oral biology · 2021Article
- Higher Risk for Sjögren's Syndrome in Patients With Fibromyalgia: A Nationwide Population-Based Cohort Study.Frontiers in immunology · 2021Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The information about comorbidities (excluding lymphoma) in primary Sjögren's syndrome (pSS) is relatively scarce. Cardiovascular disease, infections, musculoskeletal conditions or malignancy are likely the most relevant comorbid conditions in pSS. Different infections (particularly oral candidal infections) and fibromyalgia are extremely frequent in the daily clinical practice. On the other hand, the incidence of cardiovascular events and cancer in pSS is low, so information about them comes from large epidemiological studies or meta-analysis. For this reason, preclinical vascular disease is investigated by different techniques, demonstrating the presence of early atherosclerosis in pSS patients. Coronary events could be slightly more frequent in pSS than in the general population. The overall risk of malignancy in pSS patients seems to be slightly increased, likely due to excess occurrence of lymphoma. An association between pSS and thyroid cancer might exist, although it should be confirmed by further investigations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.