Evidence map›Paper›PMID 30770647›Full record

ArticleBrain and behavior2019

Nightmare disorder and REM sleep behavior disorder in inflammatory arthritis: Possibility beyond neurodegeneration.

Luca Baldelli, Olga Addimanda, Marco Burattini, Giacomo Chiaro, Veronica Brusi, Elettra Pignotti, Riccardo Meliconi, Federica Provini

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain and behavior, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Nightmare Disorder and Isolated Sleep Paralysis.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021
    Review
  4. Mental Violence: The COVID-19 Nightmare.Frontiers in psychiatry · 2020
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Luca BaldelliDepartment of Biomedical and NeuroMotor Sciences (DiBiNeM), University of Bologna, Bologna, Italy.ORCID 0000-0003-3666-1735
Olga AddimandaDepartment of Biomedical and NeuroMotor Sciences (DiBiNeM), University of Bologna, Bologna, Italy.
Marco BurattiniNeurological Clinic, Marche Polytechnic University, Ancona, Italy.
Giacomo ChiaroSleep and Epilepsy Center, Neurocenter of Southern Switzerland, Civic Hospital of Lugano, Lugano, Switzerland.
Veronica BrusiMedicine & Rheumatology Unit, IRCCS Rizzoli Ortopaedic Institute, Bologna, Italy.
Elettra PignottiMedicine & Rheumatology Unit, IRCCS Rizzoli Ortopaedic Institute, Bologna, Italy.
Riccardo MeliconiDepartment of Biomedical and NeuroMotor Sciences (DiBiNeM), University of Bologna, Bologna, Italy.
Federica ProviniDepartment of Biomedical and NeuroMotor Sciences (DiBiNeM), University of Bologna, Bologna, Italy.ORCID 0000-0001-9063-2658
Istituto Ortopedico Rizzoli · ITIstituto delle Scienze Neurologiche di Bologna · ITLaboratory for Biomedical Neurosciences · CHMarche Polytechnic University · ITUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the prevalence of REM sleep behavior disorder (RBD) in patients with inflammatory arthritis (IA) to ascertain if RBD could be an internal red flag signaling a fluctuating state of inflammation based on the theory of "protoconsciousness". MATERIALS &

methodsOne hundred and three patients with a confirmed diagnosis of IA were consecutively recruited. The patients underwent general (IA activity, functional status, laboratory tests) and neurological evaluations. A neurologist investigated RBD and REM sleep parasomnias in a semi-structured interview. Sleep quality was assessed with the Pittsburgh Sleep Quality Index, while the risk of obstructive sleep apnea syndrome (OSAS) was evaluated with the Berlin questionnaire. Beck Depression Inventory II and State-Trait Anxiety Inventory investigated depression and anxiety.

resultsPatients had a mean age of 53.7 ± 14.6 years, 65% were women; 57.3% were in a clinically active phase of IA. Two women fulfilled ICSD-3 criteria for RBD appearing 11 years after and 20 years before IA onset respectively. 31 patients scored positive for nightmare disorder (ND), 8 for recurrent isolated sleep paralysis. 65 (63.1%) patients reported poor sleep quality and 25 (24.3%) resulted at high risk for OSAS. 32 (31.0%) patients scored positively for depression or anxiety.

conclusionsThe prevalence of RBD in patients with IA did not differ from that in the general population, whereas ND presented a 2-fold increased prevalence. Whether RBD can be considered a red flag signaling an internal danger remains an open question, while ND may be a new player in this intriguing relation.

Indexed as

ArthritisDreamsNight TerrorsAdultAgedFemaleHumansMaleMiddle AgedPrevalenceREM Sleep Behavior DisorderRisk FactorsSleepSleep Apnea, ObstructiveInflammatory arthritisNeurodegenerationNightmaresPrevalenceRBDSleep

Identifiers

PMID30770647
PMCPMC6422707
OpenAlexW2914447896

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.