Evidence map›Paper›PMID 30770471›Full record

ArticleThe Journal of biological chemistry2019

Cholesterol depletion inhibits Na

Alvaro Garcia, Bogdan Lev, Khondker R Hossain, Amy Gorman, Dil Diaz, Thi Hanh Nguyen Pham, Flemming Cornelius, Toby W Allen, Ronald J Clarke

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

  1. Gangliosides in molecular interactions and cell regulation.The Journal of biological chemistry · 2026
    Review
  2. Article
  3. Review
  4. Analysis of cholesterol-recognition motifs of the plasma membrane CaJournal of bioenergetics and biomembranes · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Naked mole-rats suppress energy metabolism and modulate membrane cholesterol in chronic hypoxia.American journal of physiology. Regulatory, integrative and comparative physiology · 2020
    Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 5 countries.

Alvaro GarciaFrom the School of Chemistry, University of Sydney, Sydney, NSW 2006, Australia; The University of Sydney Nano Institute, Sydney, NSW 2006, Australia.
Bogdan Levthe School of Science, RMIT University, Melbourne, VIC 3001, Australia.
Khondker R HossainFrom the School of Chemistry, University of Sydney, Sydney, NSW 2006, Australia.
Amy GormanFrom the School of Chemistry, University of Sydney, Sydney, NSW 2006, Australia; the Department of Chemistry, University of York, Heslington, York YO10 5DD, United Kingdom.
Dil DiazFrom the School of Chemistry, University of Sydney, Sydney, NSW 2006, Australia.
Thi Hanh Nguyen PhamFrom the School of Chemistry, University of Sydney, Sydney, NSW 2006, Australia.
Flemming Corneliusthe Department of Biomedicine, University of Aarhus, DK-8000 Aarhus C, Denmark.
Toby W Allenthe School of Science, RMIT University, Melbourne, VIC 3001, Australia; the Department of Chemistry, University of California, Davis, California 95616.
Ronald J ClarkeFrom the School of Chemistry, University of Sydney, Sydney, NSW 2006, Australia; The University of Sydney Nano Institute, Sydney, NSW 2006, Australia. Electronic address: ronald.clarke@sydney.edu.au.
The University of Sydney · AUAarhus University · DKMIT University · MKRMIT University · AU

Funding

YEAST ER MOLECULAR CHAPERONE TRANSLOCATION: GENOME DATABANK HOMOLOGSP41RR006009 · NCRR · MELLON PITTS CORPORATION (MPC CORP) · PI ROPELEWSKI, ALEXANDER J · 1990 to 2011
$22.0M
Predictive multiscale in silico cardio-pharmacologyU01HL126273 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CLANCY, COLLEEN E · 2015 to 2019
$3.8M
NCRR NIH HHS P41 RR006009NHLBI NIH HHS U01 HL126273
6 · The paper itself

Abstract

Cholesterol's effects on Na

Indexed as

CholesterolMolecular Dynamics SimulationSodium-Potassium-Exchanging ATPaseAdenosine TriphosphateAnimalsbeta-CyclodextrinsCell MembraneEnzyme StabilitySwineAdenosine Triphosphatebeta-CyclodextrinsCholesterolmethyl-beta-cyclodextrinSodium-Potassium-Exchanging ATPasecholesterollipid-protein interactionlipid-protein interactionsmethyl-β-cyclodextrinmolecular dynamicsNa+/K+-ATPasepartial reaction kineticspre-steady-state kineticssteady-state activity

Identifiers

PMID30770471
PMCPMC6463725
OpenAlexW2914541321

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.