Evidence map›Paper›PMID 30770447›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

TRPM7 is the central gatekeeper of intestinal mineral absorption essential for postnatal survival.

Lorenz Mittermeier, Lusine Demirkhanyan, Benjamin Stadlbauer, Andreas Breit, Camilla Recordati, Anne Hilgendorff, Masayuki Matsushita, Attila Braun, David G Simmons, Eleonora Zakharian and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
9.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 113 citations in OpenAlex.

  1. Trial
  2. Renal TRPM6 but not Kv1.1 is required for magnesium homeostasis in mice.American journal of physiology. Renal physiology · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. ZIP3 is essential for the encephalitogenic function of pTh17 cells by regulating intracellular zinc levels.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. MgJournal of cellular physiology · 2025
    Article
  13. Review
  14. Unlocking TRPM7 interactions: A database-driven quest.Computational and structural biotechnology journal · 2025
    Review
  15. Article
  16. Article
  17. Review
  18. TRP Channels in Stroke.Neuroscience bulletin · 2024
    Review
  19. Article
  20. TRPM channels in health and disease.Nature reviews. Nephrology · 2024
    Review

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 5 countries.

Lorenz MittermeierWalther-Straub Institute of Pharmacology and Toxicology, Ludwig-Maximilians-Universität München, Munich 80336, Germany.
Lusine DemirkhanyanDepartment of Cancer Biology and Pharmacology, University of Illinois College of Medicine, Peoria, IL 61605.
Benjamin StadlbauerWalther-Straub Institute of Pharmacology and Toxicology, Ludwig-Maximilians-Universität München, Munich 80336, Germany.
Andreas BreitWalther-Straub Institute of Pharmacology and Toxicology, Ludwig-Maximilians-Universität München, Munich 80336, Germany.
Camilla RecordatiMouse and Animal Pathology Laboratory, Filarete Foundation, 20139 Milan, Italy.
Anne HilgendorffCenter for Comprehensive Developmental Care, Integrated Social Pediatric Center, Dr. von Hauner Children's Hospital, University Hospital, Ludwig-Maximilians-Universität München, Munich 80337, Germany.
Masayuki MatsushitaDepartment of Molecular and Cellular Physiology, Graduate School of Medicine, University of the Ryukyus, Okinawa 903-0215, Japan.
Attila BraunInstitute of Experimental Biomedicine, University Hospital Würzburg, Würzburg 97080, Germany.
David G SimmonsSchool of Biomedical Sciences, University of Queensland, QLD 4072, Australia.ORCID 0000-0002-4115-9371
Eleonora ZakharianDepartment of Cancer Biology and Pharmacology, University of Illinois College of Medicine, Peoria, IL 61605.
Thomas GudermannWalther-Straub Institute of Pharmacology and Toxicology, Ludwig-Maximilians-Universität München, Munich 80336, Germany; Thomas.Gudermann@lrz.uni-muenchen.de vladimir.chubanov@lrz.uni-muenchen.de.
Vladimir ChubanovWalther-Straub Institute of Pharmacology and Toxicology, Ludwig-Maximilians-Universität München, Munich 80336, Germany; Thomas.Gudermann@lrz.uni-muenchen.de vladimir.chubanov@lrz.uni-muenchen.de.ORCID 0000-0002-6042-4193
Ludwig-Maximilians-Universität München · DEGerman Center for Lung Research · DEUniversity of Illinois Urbana-Champaign · USFondazione Filarete · ITThe University of Queensland · AUUniversitätsklinikum Würzburg · DEUniversity of the Ryukyus · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zn

Indexed as

AnimalsCalciumGene Knockout TechniquesHomeostasisIntestinal MucosaKidneyMagnesiumMiceMice, KnockoutMineralsTRPM Cation ChannelsZincCalciumMagnesiumMineralsTrpm7 protein, mouseTRPM Cation ChannelsZinccalciummagnesiumTRP channelsTRPM7zinc

Identifiers

PMID30770447
PMCPMC6410795
OpenAlexW2911908266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.