Evidence map›Paper›PMID 30769939›Full record

ArticleInternational journal of molecular sciences2019

A Novel Rare Missense Variation of the

Sara Frade-Proud'Hon-Clerc, Thomas Smol, Frédéric Frenois, Olivier Sand, Emmanuel Vaillant, Véronique Dhennin, Amélie Bonnefond, Philippe Froguel, Mathurin Fumery, Nathalie Guillon-Dellac and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02851134 (Search for New Genetic Mutations Major Effect in Crohn's Disease), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02851134 completednot on this map

Search for New Genetic Mutations Major Effect in Crohn's Disease

TypeobservationalSponsorUniversity Hospital, LilleRan2015 to 2018Enrolled20ConditionsCrohn DiseaseArmsgenetic analysis, blood and stools samples
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Autophagy and its role in gastrointestinal diseases.World journal of gastroenterology · 2024
    Article
  3. Review
  4. Review
  5. Observational
  6. MiR-146aGut pathogens · 2020
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Sara Frade-Proud'Hon-ClercEA 2694-Santé Publique: épidémiologie et qualité des soins, University Lille, CHU Lille, F-59000 Lille, France. sara.frade@chru-lille.fr.
Thomas SmolEA 7364-RADEME-Maladies RAres du Developpement embryonnaire et du MEtabolisme, University Lille, F-59000 Lille, France. Thomas.SMOL@chru-lille.fr.ORCID 0000-0002-0119-5896
Frédéric FrenoisEA 7364-RADEME-Maladies RAres du Developpement embryonnaire et du MEtabolisme, University Lille, F-59000 Lille, France. Frederic.FRENOIS@chru-lille.fr.
Olivier SandCNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, F-59000 Lille, France. Olivier.sand@cnrs.fr.
Emmanuel VaillantCNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, F-59000 Lille, France. Emmanuel.Vaillant@cnrs.fr.
Véronique DhenninCNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, F-59000 Lille, France. veronique.dhennin@cnrs.fr.ORCID 0000-0003-2698-5955
Amélie BonnefondCNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, F-59000 Lille, France. Amelie.bonnefond@cnrs.fr.
Philippe FroguelCNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, F-59000 Lille, France. philippe.froguel@cnrs.fr.
Mathurin FumeryRegistre Epimad, Gastroenterology Unit, Amiens University Hospital, F-80054 Amiens, France. fumery.mathurin@chu-amiens.fr.
Nathalie Guillon-DellacRegistre Epimad, Service de Santé Publique, d'Epidémiologie, d'Economie de la Santé et de la Prévention, Maison Régionale de la Recherche Clinique, CHU Lille, F-59000 Lille, France. nathalie.guillon@chru-lille.fr.
Corinne Gower-RousseauRegistre Epimad, Service de Santé Publique, d'Epidémiologie, d'Economie de la Santé et de la Prévention, Maison Régionale de la Recherche Clinique, CHU Lille, F-59000 Lille, France. corinne.gower@chru-lille.fr.
Francis VasseurEA 2694-Santé Publique: épidémiologie et qualité des soins, University Lille, CHU Lille, F-59000 Lille, France. francis.vasseur@univ-lille2.fr.
Centre National de la Recherche Scientifique · FRUniversité de Lille · FRInserm · FRCentre Hospitalier Universitaire Amiens-Picardie · FR

Funding

Association de l'Etude des Anomalies 174 Congénitales (AEAC) none
6 · The paper itself

Abstract

The

Indexed as

Genetic Predisposition to DiseaseAdolescentAdultAllelesChildCrohn DiseaseExome SequencingFemaleGenetic Association StudiesGenotypeHeterozygoteHumansImmunity, InnateMaleMutationMutation, MissenseNOD2 protein, humanNod2 Signaling Adaptor ProteinPeptidoglycanCrohn’s diseaseNOD2 genevariationWES

Identifiers

PMID30769939
PMCPMC6412783
OpenAlexW2901458437

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.