Evidence map›Paper›PMID 30769929›Full record

ArticleInternational journal of environmental research and public health2019

Haplotype and Haplotype-Environment Interaction Analysis Revealed Roles of SPRY2 for NSCL/P among Chinese Populations.

Ren Zhou, Mengying Wang, Wenyong Li, Siyue Wang, Hongchen Zheng, Zhibo Zhou, Yonghua Hu, Jing Li, Tao Wu, Hongping Zhu and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Association analysis between forkhead box E1 gene and non-syndromic cleft lip with or without cleft palate in Han Chinese population.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2025
    Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Ren ZhouSchool of Public Health, Peking University, Beijing 100191, China. zhouren1994@163.com.ORCID 0000-0002-5776-3100
Mengying WangSchool of Public Health, Peking University, Beijing 100191, China. mywang@bjmu.edu.cn.ORCID 0000-0003-0162-5355
Wenyong LiSchool of Public Health, Peking University, Beijing 100191, China. lwy_edu@163.com.
Siyue WangSchool of Public Health, Peking University, Beijing 100191, China. yzmagiw@163.com.
Hongchen ZhengSchool of Public Health, Peking University, Beijing 100191, China. zhc_1995@163.com.
Zhibo ZhouSchool of Stomatology, Peking University, Beijing 100081, China. zzbooo@126.com.
Yonghua HuSchool of Public Health, Peking University, Beijing 100191, China. yhhu@bjmu.edu.cn.
Jing LiSchool of Public Health, Peking University, Beijing 100191, China. jli@bjmu.edu.cn.
Tao WuSchool of Public Health, Peking University, Beijing 100191, China. zhuhongping@cndent.com.
Hongping ZhuSchool of Stomatology, Peking University, Beijing 100081, China. twu@bjmu.edu.cn.
Terri H BeatySchool of Public Health, Johns Hopkins University, Baltimore, MD 21218, USA. tbeaty1@jhu.edu.
Peking University · CNJohns Hopkins University · US

Funding

International Consortium to Identify Genes and Interactions Controlling Oral ClefU01DE018993 · NIDCR · JOHNS HOPKINS UNIVERSITY · PI BEATY, TERRI H · 2007 to 2008
$1.6M
NIDCR NIH HHS U01 DE018993
6 · The paper itself

Abstract

Non-syndromic cleft lip with or without cleft palate (NSCL/P) is one of common birth defects in China, with genetic and environmental components contributing to the etiology. Genome wide association studies (GWASs) have identified

Indexed as

Asian PeopleChinaCleft LipCleft PalateDietary SupplementsFemaleGene-Environment InteractionGenome-Wide Association StudyHaplotypesHumansIntracellular Signaling Peptides and ProteinsMaleMembrane ProteinsMothersPolymorphism, Single NucleotideTobacco Smoke PollutionIntracellular Signaling Peptides and ProteinsMembrane ProteinsSPRY2 protein, humanTobacco Smoke PollutionVitaminscase-parent trioscleft lip and palategene-environmental interactiongenetic association studyhaplotypes

Identifiers

PMID30769929
PMCPMC6406689
OpenAlexW2913162191

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.