Evidence map›Paper›PMID 30769904›Full record

ArticleInternational journal of molecular sciences2019

Platinum(II)

Daniele Florio, Anna Maria Malfitano, Sarah Di Somma, Carolin Mügge, Wolfgang Weigand, Giarita Ferraro, Ilaria Iacobucci, Maria Monti, Giancarlo Morelli, Antonello Merlino and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Mechanism of Metal Complexes in Alzheimer's Disease.International journal of molecular sciences · 2024
    Review
  5. Article
  6. Article
  7. Peptide-Based Materials That Exploit Metal Coordination.International journal of molecular sciences · 2022
    Review
  8. Insights into Network of Hot Spots of Aggregation in Nucleophosmin 1.International journal of molecular sciences · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Daniele FlorioDepartment of Pharmacy, University of Naples Federico II, Napoli 80134, Italy. floriodaniele1@gmail.com.
Anna Maria MalfitanoDepartment of Translational Medical Science, University of Naples Federico II, Napoli 80131, Italy. annamaria.malfitano@unina.it.
Sarah Di SommaDepartment of Translational Medical Science, University of Naples Federico II, Napoli 80131, Italy. sarah.disomma@unina.it.
Carolin MüggeInstitute for Inorganic and Analytical Chemistry, University of Jena, Jena 07743, Germany. carolin.muegge@rub.de.
Wolfgang WeigandInstitute for Inorganic and Analytical Chemistry, University of Jena, Jena 07743, Germany. wolfgang.weigand@uni-jena.de.
Giarita FerraroDepartment of Chemical Sciences, University of Naples Federico II, Napoli 80126, Italy. giarita.ferraro@gmail.com.
Ilaria IacobucciDepartment of Chemical Sciences, University of Naples Federico II, Napoli 80126, Italy. ilaria.iacobucci@unina.it.
Maria MontiDepartment of Chemical Sciences, University of Naples Federico II, Napoli 80126, Italy. montimar@unina.it.
Giancarlo MorelliDepartment of Pharmacy, University of Naples Federico II, Napoli 80134, Italy. giancarlo.morelli@unina.it.
Antonello MerlinoDepartment of Chemical Sciences, University of Naples Federico II, Napoli 80126, Italy. antonello.merlino@unina.it.
Daniela MarascoDepartment of Pharmacy, University of Naples Federico II, Napoli 80134, Italy. daniela.marasco@unina.it.
University of Naples Federico II · ITCeinge Biotecnologie Avanzate (Italy) · ITRuhr University Bochum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Platinum(II) complexes with different cinnamic acid derivatives as ligands were investigated for their ability to inhibit the aggregation process of amyloid systems derived from Aβ, Yeast Prion Protein Sup35p and the C-terminal domain of nucleophosmin 1. Thioflavin T binding assays and circular dichroism data indicate that these compounds strongly inhibit the aggregation of investigated peptides exhibiting IC

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAmyloidosisBenzothiazolesCell LineCinnamatesCircular DichroismCoordination ComplexesHumansLigandsNuclear ProteinsNucleophosminPeptide Termination FactorsPlatinumProtein Aggregation, PathologicalSaccharomyces cerevisiae ProteinsAmyloid beta-PeptidesBenzothiazolesCinnamatescinnamic acidCoordination ComplexesLigandsNPM1 protein, humanNuclear ProteinsNucleophosminPeptide Termination FactorsPlatinumSaccharomyces cerevisiae ProteinsSUP35 protein, S cerevisiaethioflavin Tamyloid aggregationanti-aggregation propertiesplatinum complexes

Identifiers

PMID30769904
PMCPMC6413125
OpenAlexW2912259266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.