Evidence map›Paper›PMID 30769763›Full record

ArticleBiomolecules2019

Non-Toxic and Ultra-Small Biosilver Nanoclusters Trigger Apoptotic Cell Death in Fluconazole-Resistant

Prateeksha, Braj Raj Singh, Vijai Kumar Gupta, Farah Deeba, Rajesh Bajpai, Vivek Pandey, Alim H Naqvi, Dalip Kumar Upreti, Nicholas Gathergood, Yueming Jiang and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Materials today. Bio · 2022
    Article
  5. PeerJ · 2021
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 6 countries.

PrateekshaHerbal Nanobiotechnology Lab, Pharmacology Division, CSIR-National Botanical Research Institute, Lucknow 226001, India. pratikschemistry@gmail.com.
Braj Raj SinghCentre of Excellence in Materials Science (Nanomaterials), Z.H. College of Engineering and Technology, Aligarh Muslim University, Aligarh 202002, India. brajviro@gmail.com.
Vijai Kumar GuptaERA Chair of Green Chemistry, Department of Chemistry and Biotechnology, Tallinn University of Technology (TUT), 12618 Tallinn, Estonia. vijaifzd@gmail.com.ORCID 0000-0003-1565-5918
Farah DeebaPlant Ecology and Climate Change Science Division, CSIR-National Botanical Research Institute, Lucknow 226001, India. farahnbri@gmail.com.
Rajesh BajpaiLichenology Laboratory, Plant Biodiversity and Conservation Biology Division, CSIR-National Botanical Research Institute, Lucknow 226001, India. bajpaienviro@gmail.com.
Vivek PandeyPlant Ecology and Climate Change Science Division, CSIR-National Botanical Research Institute, Lucknow 226001, India. v.pandey@nbri.res.in.ORCID 0000-0002-3006-7738
Alim H NaqviCentre of Excellence in Materials Science (Nanomaterials), Z.H. College of Engineering and Technology, Aligarh Muslim University, Aligarh 202002, India. aligarhnano@gmail.com.
Dalip Kumar UpretiLichenology Laboratory, Plant Biodiversity and Conservation Biology Division, CSIR-National Botanical Research Institute, Lucknow 226001, India. upretidknbri@gmail.com.
Nicholas GathergoodERA Chair of Green Chemistry, Department of Chemistry and Biotechnology, Tallinn University of Technology (TUT), 12618 Tallinn, Estonia. nicholas.gathergood@ttu.ee.
Yueming JiangKey Laboratory of Plant Resource Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China. ymjiang@scbg.ac.cn.ORCID 0000-0002-4648-9572
Hesham A El EnshasyInstitute of Bioproduct Development, Universiti Teknologi Malaysia, Johor Bahru 81310, Malaysia. henshasy@ibd.utm.my.
Essam Nageh SholkamyDepartment of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia. essam_92003@yahoo.com.
Ashraf A MostafaDepartment of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia. ashraf812@yahoo.com.
Abd El-Latif HeshamMeta-Genome Biotechnology, Genetics Department, Faculty of Agriculture, Assiut University, Assiut 71526, Egypt. hesham_egypt5@aun.edu.eg.
Brahma N SinghHerbal Nanobiotechnology Lab, Pharmacology Division, CSIR-National Botanical Research Institute, Lucknow 226001, India. vijai.gupta@taltech.ee.
National Botanical Research Institute · INTallinn University of Technology · EEKing Saud University · SAChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Silver-based nanostructures are suitable for many biomedical applications, but to be useful therapeutic agents, the high toxicity of these nanomaterials must be eliminated. Here, we biosynthesize nontoxic and ultra-small silver nanoclusters (rsAg@NCs) using metabolites of usnioid lichen (a symbiotic association of algae and fungi) that exhibit excellent antimicrobial activity against fluconazole (FCZ)-resistant

Indexed as

Antifungal AgentsCandida albicansCell DeathCell SurvivalDrug Resistance, FungalFluconazoleLichensMetal NanoparticlesParticle SizeProto-Oncogene Proteins p21(ras)Reactive Oxygen SpeciesSignal TransductionSilverSurface PropertiesAntifungal AgentsFluconazoleProto-Oncogene Proteins p21(ras)Reactive Oxygen SpeciesSilverapoptosisbiosilver nanoclustersfluconazole-resistant Candida albicansoxidative stressproteomicsRas signaling pathway

Identifiers

PMID30769763
PMCPMC6406502
OpenAlexW2913692304

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.