Evidence map›Paper›PMID 30769264›Full record

ArticleDrug and alcohol dependence2019

Electronic cigarette and tobacco use in individuals entering methadone or buprenorphine treatment.

Stephen R Baldassarri, David A Fiellin, Mary Ellen Savage, Lynn M Madden, Mark Beitel, Lara K Dhingra, Lisa Fucito, Deepa Camenga, Pooja Bollampally, Declan T Barry

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. The prevalence of electronic cigarettes vaping globally: a systematic review and meta-analysis.Archives of public health = Archives belges de sante publique · 2022
    Pooled it
  3. Trial
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  6. Article
  7. Effects of E-cigarettes on Combustible Cigarette Smoking Among Adults With Opioid Use Disorder on Buprenorphine: Single Arm ERASER Pilot Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Article
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  13. Interest in Electronic Cigarettes for Smoking Cessation Among Adults With Opioid Use Disorder in Buprenorphine Treatment: A Mixed-Methods Investigation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Stephen R BaldassarriDepartment of Internal Medicine, Section of Pulmonary, Critical Care, and Sleep Medicine, Yale School of Medicine, New Haven, CT, USA. Electronic address: stephen.baldassarri@yale.edu.
David A FiellinDepartment of Internal Medicine, Section of General Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
Mary Ellen SavageDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA; APT Foundation, New Haven, CT, USA.
Lynn M MaddenAPT Foundation, New Haven, CT, USA; Department of Internal Medicine - AIDS, Yale School of Medicine, New Haven, CT, USA.
Mark BeitelDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA; APT Foundation, New Haven, CT, USA.
Lara K DhingraDepartment of Family and Social Medicine, Albert Einstein College of Medicine, Bronx, NY, USA; MJHS Institute for Innovation in Palliative Care, New York, NY, USA.
Lisa FucitoDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Deepa CamengaAPT Foundation, New Haven, CT, USA; Department of Emergency Medicine, Yale School of Medicine, New Haven, CT, USA.
Pooja BollampallyAPT Foundation, New Haven, CT, USA; Yale School of Public Health, Department of Social and Behavioral Sciences, New Haven, CT, USA.
Declan T BarryDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA; Child Study Center, Yale School of Medicine, New Haven, CT, USA; APT Foundation, New Haven, CT, USA.
Yale University · USAlbert Einstein College of Medicine · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Drug use, Addiction and HIV Research Scholars (DAHRS)K12DA033312 · NIDA · YALE UNIVERSITY · PI Gail D'Onofrio, Patrick O'Connor · 2013 to 2026
$7.2M
Understanding Factors that Influence Electronic Cigarette Nicotine Delivery Through PET Imaging of Beta-2 Nicotinic Acetylcholine ReceptorsK23DA045957 · NIDA · YALE UNIVERSITY · PI BALDASSARRI, STEPHEN · 2018 to 2022
$983k
NCATS NIH HHS UL1 TR001863NIDA NIH HHS K12 DA033312NIDA NIH HHS K23 DA045957
6 · The paper itself

Abstract

backgroundAlthough smoking is prevalent among populations with opioid use disorder (OUD), few studies have examined electronic cigarette (EC) use in individuals seeking opioid agonist therapy (OAT). The aim of this study was to evaluate the prevalence and correlates of EC use among individuals seeking OAT.

methods782 patients seeking OAT for OUD completed surveys assessing current and past EC use, reasons for use, current and past cigarette smoking, nicotine dependence, psychiatric distress, trauma, and pain. Bivariate and multivariate models evaluated correlates of daily EC use, past-30-day EC use, and current cigarette smoking.

results6% of patients reported daily EC use, 18% reported past-30-day use, 62% reported EC use history, and 85% reported current cigarette smoking. 46% reported using ECs to quit or cut down smoking. In multivariate analyses, daily EC use was associated with higher odds of being a former smoker (OR 21; CI 1.7-273) and lower odds of ever smoking more than 100 cigarettes (OR 0.07; CI 0.01-0.32), while EC use in the past 30 days was associated with lower odds of being Caucasian (OR 0.55; CI 0.34-0.89), ever smoking more than 100 cigarettes (OR 0.13; CI 0.02-0.67), and history of chronic pain (OR 0.59; CI 0.38-0.90), and higher odds of reporting psychiatric distress (OR 1.5; CI 1.1-2.2).

conclusionsEC use is common among people with OUD who smoke cigarettes. Those with daily use had higher odds of being former smokers than current smokers. Interventions using ECs may be effective to help reduce harms and mortality in OUD.

Indexed as

AdultBuprenorphineElectronic Nicotine Delivery SystemsFemaleHumansMaleMethadoneMiddle AgedOdds RatioOpiate Substitution TreatmentOpioid-Related DisordersPrevalenceSurveys and QuestionnairesTobacco SmokingTobacco Use DisorderVapingBuprenorphineMethadoneElectronic cigaretteMethadoneNicotineOpioidSmokingTobacco

Identifiers

PMID30769264
PMCPMC6637405
OpenAlexW2909796288

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.