ArticleAngewandte Chemie (International ed. in English)2019
Efficient Access to Deuterated and Tritiated Nucleobase Pharmaceuticals and Oligonucleotides using Hydrogen-Isotope Exchange.
Article in Angewandte Chemie (International ed. in English), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Skeletal editing approach forCommunications chemistry · 2026Article
- Scalable reductive deuteration of (Hetero)Aryl chlorides with DNature communications · 2025Article
- Selective H/D Exchange in E-H (E = Si, Ge, Sn) Bonds Catalyzed by 1,2,3-Triazolylidene-Stabilized Nickel Nanoparticles.Inorganic chemistry · 2025Article
- Electroreductive deuteroarylation of alkenes enabled by an organo-mediator.Chemical science · 2024Article
- Radiolabelling small and biomolecules for tracking and monitoring.RSC advances · 2022Review
- Manganese-Catalysed Deuterium Labelling of Anilines and Electron-Rich (Hetero)Arenes.Angewandte Chemie (International ed. in English) · 2022Article
- Copper-catalysed low-temperature water-gas shift reaction for selective deuteration of aryl halides.Chemical science · 2021Article
- Organophotocatalytic selective deuterodehalogenation of aryl or alkyl chlorides.Nature communications · 2021Article
- Transition-Metal-Free Carbon Isotope Exchange of Phenyl Acetic Acids.Angewandte Chemie (International ed. in English) · 2020Article
- Hydrogen Isotope Exchange Catalyzed by Ru Nanocatalysts: Labelling of Complex Molecules Containing N-Heterocycles and Reaction Mechanism Insights.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020Article
- Efficient Access to Deuterated and Tritiated Nucleobase Pharmaceuticals and Oligonucleotides using Hydrogen-Isotope Exchange.Angewandte Chemie (International ed. in English) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
A general approach for the efficient hydrogen-isotope exchange of nucleobase derivatives is described. Catalyzed by ruthenium nanoparticles, using mild reaction conditions, and involving either D
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.