Evidence map›Paper›PMID 30768391›Full record

ArticleJournal of the American Academy of Child and Adolescent Psychiatry2019

Attention-Deficit/Hyperactivity Disorder, School Performance, and Effect of Medication.

Andreas Jangmo, Amanda Stålhandske, Zheng Chang, Qi Chen, Catarina Almqvist, Inna Feldman, Cynthia M Bulik, Paul Lichtenstein, Brian D'Onofrio, Ralf Kuja-Halkola and 1 more

Abstract read
In one paragraph

Article in Journal of the American Academy of Child and Adolescent Psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  11. Psychiatric diagnosis on the edge: is there evidence of benefit?European child & adolescent psychiatry · 2026
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  18. Prevalence of ADHD Among Saudi Children and Adolescents.International journal of environmental research and public health · 2026
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  19. Article
  20. Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Andreas JangmoKarolinska Institutet, Stockholm, Sweden. Electronic address: andreas.jangmo@ki.se.
Amanda StålhandskeKarolinska Institutet, Stockholm, Sweden; Child and Adolescent Clinic, Stockholm County Council, Stockholm, Sweden.
Zheng ChangKarolinska Institutet, Stockholm, Sweden.
Qi ChenKarolinska Institutet, Stockholm, Sweden.
Catarina AlmqvistKarolinska Institutet, Stockholm, Sweden; Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
Inna FeldmanUppsala University, Uppsala, Sweden.
Cynthia M BulikKarolinska Institutet, Stockholm, Sweden; University of North Carolina at Chapel Hill, NC.
Paul LichtensteinKarolinska Institutet, Stockholm, Sweden.
Brian D'OnofrioKarolinska Institutet, Stockholm, Sweden; Indiana University, Bloomington, IN.
Ralf Kuja-HalkolaKarolinska Institutet, Stockholm, Sweden.
Henrik LarssonKarolinska Institutet, Stockholm, Sweden; School of Medical Sciences, Örebro University, Örebro, Sweden.

Funding

Risks and Benefits of ADHD Medication for Psychiatric and Neurologic ProblemsR01MH102221 · NIMH · TRUSTEES OF INDIANA UNIVERSITY · PI D'ONOFRIO, BRIAN M, LARSSON, HENRIK · 2014 to 2017
$1.7M
NIMH NIH HHS R01 MH102221
6 · The paper itself

Abstract

objectiveIndividuals with attention-deficit/hyperactivity disorder (ADHD) are at increased risk for poor school performance, and pharmacological treatment of ADHD may have beneficial effects on school performance. Conclusions from previous research have been limited by small sample sizes, outcome measures, and treatment follow-up. The current study analyzed school performance in students with ADHD compared to students without ADHD, and the association between pharmacological treatment of ADHD and school performance.

methodA linkage of Swedish national registers covering 657,720 students graduating from year 9 of compulsory school provided measures of school performance, electronically recorded dispensations of ADHD medication, and potentially confounding background factors such as parental socioeconomic status. Primary measures of school performance included student eligibility to upper secondary school and grade point sum.

resultsADHD was associated with substantially lower school performance independent of socioeconomic background factors. Treatment with ADHD medication for 3 months was positively associated with all primary outcomes, including a decreased risk of no eligibility to upper secondary school, odds ratio = 0.80, 95% confidence interval (CI) = 0.76-0.84, and a higher grade point sum (range, 0.0-320.0) of 9.35 points, 95% CI = 7.88-10.82; standardized coefficient = 0.20.

conclusionADHD has a substantial negative impact on school performance, whereas pharmacological treatment for ADHD is associated with higher levels in several measures of school performance. Our findings emphasize the importance of detection and treatment of ADHD at an early stage to reduce the negative impact on school performance.

Indexed as

Academic SuccessAdolescentAttention Deficit Disorder with HyperactivityCentral Nervous System AgentsEducational StatusFemaleHumansLogistic ModelsMaleParentsRegistriesSchoolsSocioeconomic FactorsStudentsSwedenTreatment OutcomeCentral Nervous System AgentsADHDmedicationschool performancetreatment

Identifiers

PMID30768391
PMCPMC6541488

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.